Protein Info for Shewana3_1922 in Shewanella sp. ANA-3

Annotation: sodium/sulphate symporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 38 to 68 (31 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 119 to 148 (30 residues), see Phobius details amino acids 168 to 190 (23 residues), see Phobius details amino acids 213 to 236 (24 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 281 to 301 (21 residues), see Phobius details amino acids 313 to 333 (21 residues), see Phobius details amino acids 354 to 379 (26 residues), see Phobius details amino acids 392 to 415 (24 residues), see Phobius details amino acids 435 to 455 (21 residues), see Phobius details signal peptide" amino acids 27 to 27 (1 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 12 to 461 (450 residues), 88.1 bits, see alignment E=7e-29 PF03600: CitMHS" amino acids 45 to 400 (356 residues), 104.7 bits, see alignment E=5.8e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1922)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWI4 at UniProt or InterPro

Protein Sequence (462 amino acids)

>Shewana3_1922 sodium/sulphate symporter (RefSeq) (Shewanella sp. ANA-3)
MGKLSIKQWLVFSAMLVAVLLAMFPLQQHPALFSYSASVVLITLLFWSTGFIPPFMAGLI
FFALATIFKLIDPSALFSGFGSAAVWLIISGFVIGSAISESGLSRRLAAVIAPALTMSYP
RMIAGLVISAMLLGFVMPSSVGRAVVMLPIGMALADQLGFSRGSNGRIGIATALALACNM
PSLAVLPANIPNMILAGASENLFNVHFGYAEYLFLHFPILGLLKSAIIVALVVYLFPAKI
NKNQIAAATDIEAYDVVKQVKLALLLIITLLFWITDSWHGINPAWVGLTTAIILLLPKWG
IIEPKRFNQSVDFSTVIFVAAALGLGALVNQSGLGSALGQAFSQYLPLSQGASFLNFISL
SLISTLTGLVATVPGVPTVLTPMAADLANATGFSLPAVLMTQVIGFSTVIFPYQAPPLIL
AMQLSQESLAHLLKVTLPLALITLLVLMPLDYLWWHLLGWIS