Protein Info for Shewana3_1726 in Shewanella sp. ANA-3

Annotation: sodium:dicarboxylate symporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 48 to 72 (25 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 194 to 218 (25 residues), see Phobius details amino acids 227 to 248 (22 residues), see Phobius details amino acids 268 to 284 (17 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 337 to 380 (44 residues), see Phobius details PF00375: SDF" amino acids 11 to 407 (397 residues), 448.4 bits, see alignment E=1.1e-138

Best Hits

Swiss-Prot: 33% identical to DCTA_AZOC5: C4-dicarboxylate transport protein (dctA) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1726)

Predicted SEED Role

"Proton/glutamate symport protein @ Sodium/glutamate symport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KVZ0 at UniProt or InterPro

Protein Sequence (437 amino acids)

>Shewana3_1726 sodium:dicarboxylate symporter (RefSeq) (Shewanella sp. ANA-3)
MATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLK
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASL
ASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQIIIFAVIFGFAIAHIGERGKRV
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHA
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASF
TLPLGATINMDGTAIMQGVATVFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLI
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNETVFNNT
QAGKVASNFDEQVHKVE