Protein Info for Shewana3_1595 in Shewanella sp. ANA-3

Annotation: PKD domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 948 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00932: LTD" amino acids 20 to 128 (109 residues), 63.9 bits, see alignment E=3.5e-21 PF18911: PKD_4" amino acids 786 to 864 (79 residues), 68.8 bits, see alignment E=6.8e-23 PF00801: PKD" amino acids 794 to 861 (68 residues), 58.6 bits, see alignment 1e-19

Best Hits

KEGG orthology group: K07004, (no description) (inferred from 100% identity to shn:Shewana3_1595)

Predicted SEED Role

"Extracellular deoxyribonuclease PA3909 (required for catabolism of external DNA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KVL0 at UniProt or InterPro

Protein Sequence (948 amino acids)

>Shewana3_1595 PKD domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MFNNKTLLALAISGVCGFAHAADNLIITEYVEGSSNNKAIELYNPTASSIDLSQYQLRFY
FNGSTTVGTTIALTGTLAAGATHVVADNDASADILAVTNQQSSASFFNGDDAIVLTYQDQ
VIDSLGQVGVDPGSEWGSGDLSTQDNTLRRNPEQLIADTIIDDVVTFNTWLGFAKDDISD
LGKFSAGTPTDPVEPPPSSLACGEASTPIHALQGSTNVSPLNGQTLVVEAIVVSNQEAGL
KGIFVQMADNEADNDPQTSEGVFVYTGNAPTGYVAGDRVRLKAKVTEYQGLTELTTVADH
KLCAAGQTLPTAAVVTLPVNSSDDFEPFEGMRVRFSQDLVVNEVYNLGRYGEISLGSSRH
FIGTQVAAPGTDALAVTAANLKDSILLDDGLTAQNPDPVIFPAPGLSASNTVRVGDKATS
LTGVMHYGFNLYRIMPTEPVNFVAENPRPQSPVLAEGGNLKVASFNVLNYFNGDGQGSGF
PTARGANTLSEFERQKAKIVSAMVGTSADVFGLMEIENDGFGANSAIADLVAGLNAAVGE
NRYAYVIPKVNGSNLSAIGTDAITVGLIYRSDKVSPQGDARILSSANSPLDDAGQPLFDD
SKNRPMLTQAFVLNGSEESVVVAVNHLKSKGSECAGDPDMNDGQGNCNITRTRAATAAGQ
WIAEQYPEQGVLLIGDLNSYAKEDPLSALANAGFSELFAKLEKANPYSYVFSGESGQLDH
ALANTALVDKVVDVTEWHINTDEPRVLDYNEEFKTAAQVQDLYASDAYRSSDHDPVVISL
LLEAENVAPEASFTQLVNGASVQLTSTSIDSDGQIVSTEWDFGDNSQAMGESVSHTYAQT
GDYLVTLTVTDNDGLSHSSSQMVSVVVENVKKPPVAQIQHINLWLVDMFISTSYDTDGVI
KQHKWKFDNGSRASGPVVFRQARRGLHTVELTVKDNDKLTDTTSLTFR