Protein Info for Shewana3_1545 in Shewanella sp. ANA-3

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF10672: Methyltrans_SAM" amino acids 19 to 299 (281 residues), 325.2 bits, see alignment E=3.5e-101 PF03602: Cons_hypoth95" amino acids 131 to 248 (118 residues), 32 bits, see alignment E=9.6e-12

Best Hits

KEGG orthology group: K06969, ribosomal RNA large subunit methyltransferase I [EC: 2.1.1.-] (inferred from 100% identity to shn:Shewana3_1545)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KVG0 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Shewana3_1545 hypothetical protein (RefSeq) (Shewanella sp. ANA-3)
MQRFIDALATIEVGEDATRLFHGRGGYYPGCEHLCLDWFAPVLLLTSFIPLDAAELAECQ
QAITARWQAIQPNRLLNLVYQYRSAGETFSQVLAGEVPDPHVVTENGAQFQVHLLRGQNH
GLFLDMANGREWVRAHARHKKVLNLFAYTCGFSVAALQGGADEVVNMDMSKGALAIGKQN
HLLNGFSAGARFLGHDIFKSWGKLRKLGPYDIVVADPPSNQKGSFVATKDYVRLIRHLPE
LLAENAEVLLCLNAPELDTQFLRQQVEDAAPALEFLERLPNPAAFVDVSEEKSLKVLRYR
LKA