Protein Info for Shewana3_1471 in Shewanella sp. ANA-3

Annotation: ATP-NAD/AcoX kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01513: NAD_kinase
  • amino acids 7 to 169 (163 residues), 70.8 bits, E=2.1e-23
• PF00781: DAGK_cat
  • amino acids 84 to 143 (60 residues), 22.3 bits, E=1.2e-08
• PF20143: NAD_kinase_C
  • amino acids 235 to 370 (136 residues), 59.2 bits, E=5.5e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1471)

Predicted SEED Role

"ATP-NAD kinase (EC 2.7.1.23)" (EC 2.7.1.23)

MetaCyc Pathways

• NADP biosynthesis (1/1 steps found)
• NAD phosphorylation and transhydrogenation (1/2 steps found)
• cytosolic NADPH production (yeast) (3/5 steps found)
• mitochondrial NADPH production (yeast) (3/5 steps found)
• superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) (5/8 steps found)
• NAD phosphorylation and dephosphorylation (1/3 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.23

Use Curated BLAST to search for 2.7.1.23

Sequence Analysis Tools

See A0KV86 at UniProt or InterPro

Protein Sequence (380 amino acids)

>Shewana3_1471 ATP-NAD/AcoX kinase (RefSeq) (Shewanella sp. ANA-3)
MIRFRLGLVINPLAGLGGSVGLKGSDGVAEQALALGAEPKAIKRMMQALEVIVPFANDIE
IITASGVMGEDAANALGFNSRVVYQTPEKTQAVDTQAVVRTLLNEPLDLLLFAGGDGTAR
DVYSVFEQAVIDDKLPVLGVPAGVKIHSGVYGITPHAAGMVVKMLLEGELVSLMSADVMD
IDEVAFRQGTVRAKRFGELLVPAEPRYVQAVKMGGKEVDELVLADIAADVIQQMEDELYI
MGSGSTVAFVMEELGLDNTLLGVDLIQDKILVASDLTAKQLLDFTQDKPAKLVITLIGGQ
GHILGRGNQQLSPELIRRLGKDNIIILATKTKLKALEGRPLIVDSGDPQLDRELCGYYKV
TTGYHDYVMYQVANPDYSDL