Protein Info for Shewana3_1465 in Shewanella sp. ANA-3

Annotation: peptidase M16 domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 929 PF00675: Peptidase_M16" amino acids 27 to 144 (118 residues), 99.2 bits, see alignment E=4.4e-32 PF05193: Peptidase_M16_C" amino acids 187 to 360 (174 residues), 99.3 bits, see alignment E=5.1e-32 amino acids 652 to 830 (179 residues), 53.9 bits, see alignment E=4.2e-18 PF16187: Peptidase_M16_M" amino acids 371 to 647 (277 residues), 290.7 bits, see alignment E=2e-90 PF22456: PqqF-like_C_4" amino acids 750 to 849 (100 residues), 115.3 bits, see alignment E=2.5e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1465)

Predicted SEED Role

"Protease III precursor (EC 3.4.24.55)" (EC 3.4.24.55)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KV80 at UniProt or InterPro

Protein Sequence (929 amino acids)

>Shewana3_1465 peptidase M16 domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MQASQSIYKSPNDHRQYRYLVLDNALRVLLVEDFDASQAAASMAVAVGHFDDPVDRPGMA
HFLEHMLFLGTEKFPDSGEYHAFINQHGGSNNAWTGTEHTNFFFTINADVFADSLDRFSQ
FFIAPKFDLDLVDRERQAIESEFSLKLKDDIRRTYQVLKETVNQQHPFSKFSVGNLVTLG
GEQAQVRSELLAFYQSHYSANLMTLCLVAPMPLDELQSLAAQYFSAVRNLNLVKQYPDVP
LFSENELLKQINIIPLKEQKRLSISFNFPGIDHYYKRKPLTYISHILGNESKGSLLSYLK
EQGLVNNLSAGGGVNGYNFKDYCIGLQLTDKGVANIDDIVCSCFEYIELIKNQGLEDWRY
LERANLLKMAFRYQEQVKSLDLASHLSINMHHYEVEDLVFGDYRMDGLDIDETLDLLRLM
TPQNMRLQLIAQSVKTDRKANWYHTPYQVLPIKPESLARWQVTHIRPELQLPAANPFIVA
DSIARPDKSEVAVPVIVAESTGYRIWHKKDDEFNVPKGHMYLSLDSEQASKTPKHAALTR
LYVEMLLDYLTEPTYQAEVAGLSYNIYPHQGGITLHLSGFTGNQETLLALLIQKARERNF
TEERFALIKSQLLRSWQNLAQAKPISQLFTSLTATLQKRSYEPARMAQMLENITLNDLHN
HVRAFYEKIYLEGLIYGDWLVSEAQALGKRLEHILSLVSSPSAESTRELINLTGQGTLLR
ELAIDHQDSAIIVYYQSASATPEKMALFSLLNHTMSSTFFHELRTEKQLGYMVGTGYLPL
NRHPGLIFYIQSPTTGPLHLLEAIDEFIADFNYAVMQITNEEWESTKQGLINQVMEHDAN
LKTRGQRYWVSVGNRDYQFNQRELVVEEINKLTRPDLIKFMMRKMRTKHSDRLVLFSTGS
AHAAQSELESGNMITDLKLFKQNTEKFNF