Protein Info for Shewana3_1403 in Shewanella sp. ANA-3

Annotation: amidohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1024 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01979: Amidohydro_1" amino acids 359 to 427 (69 residues), 27.8 bits, see alignment 1.5e-10 amino acids 872 to 954 (83 residues), 48.4 bits, see alignment E=8.5e-17 PF07969: Amidohydro_3" amino acids 904 to 961 (58 residues), 31.4 bits, see alignment 1.5e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_1403)

Predicted SEED Role

"Secreted enzyme, contains two amidohydrolase related domains"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KV18 at UniProt or InterPro

Protein Sequence (1024 amino acids)

>Shewana3_1403 amidohydrolase (RefSeq) (Shewanella sp. ANA-3)
MQINNKIIISCGIISSFVSHNIFAEANPISPVNKLTAFTNAELIMAPGKRLTNATLLVEN
NRIKAIIEKGDIPAAALKVDLSGYTIYPGFIDPFTDYGIEFEYPKLGLTRPVYDIKRIGG
NAENGAIHAEKEWFNYVYPNKERARDWINNGFTSVQSSKLDGIFRGTGVSLSLADKTANE
VIYRARSQPFMAFDKGTSEQDYPNSLMGSIALIRQTFADANWYNQNKHKSVNSSANAQIE
FNIAFERLDNLAEKQIVFETKNLNDLLRAANLLKEHQQPANLLASGQEYARINELKALNY
PLILPLNYPQAPDVGTDDADREVSLAELRQWERAPTNPAAVANAGIPFAFTQFGIKTEAF
WPRLRQAIAQGLSEDNALAALTTQAAEMAGTADFAGKLAPGYMADFVITKGNIFKDGQIY
SVWLQGEEQSIRSLPQAKLLGDYQLTLNNLTLDLSLEKTGKAGKTTFQGQLSSGEKSIAL
TNLKLENDGRVSFNADLSDAGIHGISRFTLWLAKDGIQGRMVDAQSRSINVAGIAIASSP
KTEQEGTPKTDAAPTLVSQLTYPNVAYGLSEAPKAEKLHIKNATLWTSDKQGILEHADLL
MANGRIEKIGQQLSTPSGYQVLDATGKHLTAGIVDEHSHIAINGGTNEGTDAVTSEVRIG
DVINPEDISIYRALAGGVTSAQLLHGSANPIGGQSQLIKMKWGESAEQLKFANAPASIKF
ALGENVKQSNWGEKFVQRFPQTRMGVKALFEETFDAAIAYEKGLKDYDDLRSSEKKKTIA
PRPSYRLQAVAEVLKQQRDVHIHSYVQSEILMFLRLAEAYHFKVQTFTHVLEGYKVASEL
AAHGAGASTFADWWAYKFEVYDAIPQNACLMQKQGVLTSINSDDYEMQRRLNQEAAKSMM
YCDMSKEDAWNMVTINPAKQLRVDEYVGSLTPGKMADIVLWNAEPLSIYAKVTQAWVEGK
RYFDRDQDQLAQQQVVAERAALIQKILSSDDNAKAGEKVTPLNEPQWHCDTHYQAWGQHH
QGAK