Protein Info for Shewana3_1390 in Shewanella sp. ANA-3

Annotation: GAF sensor signal transduction histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 PF01590: GAF" amino acids 22 to 161 (140 residues), 47.7 bits, see alignment E=2.4e-16 PF02518: HATPase_c" amino acids 344 to 452 (109 residues), 72.6 bits, see alignment E=3.7e-24

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 100% identity to shn:Shewana3_1390)

Predicted SEED Role

"Signal transduction histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KV05 at UniProt or InterPro

Protein Sequence (453 amino acids)

>Shewana3_1390 GAF sensor signal transduction histidine kinase (RefSeq) (Shewanella sp. ANA-3)
MTRMLDRILFDVSRSSIIDGGDLVEASQLIVTSVCQGLKITRAGIWLWSEDHQSMHCFYL
LDNMHRQEALILTRQDYPHYFSLLDNERAIVANHAQTDGATHEFVSAYLVPNRISSLLDS
PIRHRGKMVGIICSEHQGVPREWTRDERAFASALADLFGRAMSAKEILDYQHQLKAINAD
LEVQVEQRTQELETALSDLRSIQHHLVENEKMAALGSLVAGVAHEVNTPLGIAVTSVTHC
LDEVALLKTAFEQNELDEDKFLSFINTMQDGLGLIERNLSRAAELVHNFKRTAADQSVLE
RERFNLKTYIFQIFSSLRPLMRKKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHG
FPESFTGDKSITIRVQKQDSNICMQYQDNGVGMSDEVKLKAFEPFFTTARKDGGTGLGMS
IIYNLVTQKLHGTILLASSPDQGVKVEIQIPEK