Protein Info for Shewana3_1043 in Shewanella sp. ANA-3

Annotation: phosphopentomutase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01676: Metalloenzyme
  • amino acids 2 to 395 (394 residues), 169 bits, E=7.2e-54
• TIGR01696: phosphopentomutase
  • amino acids 3 to 402 (400 residues), 556.2 bits, E=1.7e-171

Best Hits

Swiss-Prot: 100% identical to DEOB_SHESA: Phosphopentomutase (deoB) from Shewanella sp. (strain ANA-3)

KEGG orthology group: K01839, phosphopentomutase [EC: 5.4.2.7] (inferred from 100% identity to shn:Shewana3_1043)

MetaCyc: 71% identical to phosphopentomutase (Escherichia coli K-12 substr. MG1655)
Phosphopentomutase. [EC: 5.4.2.7]; 5.4.2.7 [EC: 5.4.2.7]

Predicted SEED Role

"Phosphopentomutase (EC 5.4.2.7)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 5.4.2.7)

MetaCyc Pathways

• superpathway of purine deoxyribonucleosides degradation (7/7 steps found)
• purine ribonucleosides degradation (6/6 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (6/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (3/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.7

Sequence Analysis Tools

See A0KU09 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Shewana3_1043 phosphopentomutase (RefSeq) (Shewanella sp. ANA-3)
MKRTVIMMLDSFGVGAAGDAAKFGDLGSDTFGHIAKACAEGEADIGREGPLTLPNLARLG
LAHAAMESTGAFAPGFADNVELIGAYGHAQELSSGKDTPSGHWEMAGVPVLFEWGYFSEH
QNSFPKELTDKILARAGLDGFLGNCHASGTTILEELGEEHMRSGKPIFYTSADSVFQIAC
HEGTFGLENLYRLCEIAREELEPYNIGRVIARPFDGTGPSDFARTGNRKDYSLEPPAKTV
LDKLKAAGGEVVSVGKIADIYAYCGITKKVKANGLEALFDATLAEVKSAGENTIVFTNFV
DFDSHYGHRRDVAGYAKGLEYFDSRLPEMLALLDEDDLLILTADHGCDPTWQGTDHTREY
VPVLAYGAGLKAGSLGRRNSFADIGQSIASYFKLEPMEYGESFI