Protein Info for Shewana3_1040 in Shewanella sp. ANA-3

Annotation: nucleoside-specific channel-forming protein, Tsx (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03502: Channel_Tsx" amino acids 32 to 279 (248 residues), 321 bits, see alignment E=3.2e-100

Best Hits

Swiss-Prot: 60% identical to OMPK_VIBPA: Outer membrane protein OmpK (ompK) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

KEGG orthology group: K05517, nucleoside-specific channel-forming protein (inferred from 100% identity to shn:Shewana3_1040)

Predicted SEED Role

"Outer membrane protein OmpK"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KU06 at UniProt or InterPro

Protein Sequence (279 amino acids)

>Shewana3_1040 nucleoside-specific channel-forming protein, Tsx (RefSeq) (Shewanella sp. ANA-3)
MKNVKTLALAATAVAAMSGNAFAADRSDLHGSDYKWMQFNAMYSIGEKPDNPASGDQHNY
LEMEFGGRSGIFDLYGYVDVFNLANENTKDGDKNPGSGTSKLFMKFAPRVSIDALTGKDL
SFGPVQEVYFSTLFNWDGLNGEGVNSTFWGVGADVNVPWLGKTGMNLYGYYDMNAKEWNG
YQFSANWFKPFYFFDNKSFLSFQGYIDYQFGADEDKTAFVPKTSNGGNIFFGLYWHSDRY
ALGYGLKGFKDVYLLEDGAGALALESTGWSHYLSATYKF