Protein Info for Shewana3_0638 in Shewanella sp. ANA-3

Updated annotation (from data): smc-like chromosome partitioning protein (DUF3584)
Rationale: This gene has a conserved motility defect. and some close homologs are important for resisting cisplatin. DUF3584 is distantly related to smc proteins.
Original annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1223 transmembrane" amino acids 1118 to 1135 (18 residues), see Phobius details PF12128: DUF3584" amino acids 8 to 1195 (1188 residues), 1814.7 bits, see alignment E=0

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_0638)

Predicted SEED Role

"FIG020374: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KSV7 at UniProt or InterPro

Protein Sequence (1223 amino acids)

>Shewana3_0638 smc-like chromosome partitioning protein (DUF3584) (Shewanella sp. ANA-3)
MPSLIRIVLIDTHLPGVVELALNGHTNICGTNASGKTTLQRLVPVFYGEYPSRVVPSTRD
SFERWYLPHDSSYIIYEYQKADGLLYQAVLASAGDGKGVNYRFIGKGFELSDYIKTQNGD
TILCHTMAELGRELKRQGVATTNLLNTREYRAIIQNDRTLLSTGSNRSELRAYAHQFALC
EGEHSLRHIEKLAKAVHSKEGKMETVKSMIAAILEEDGVNPPSSRLNPQRVEAWIRESQL
IQGFEVIRPEFEKLEQEFNQLLSAEMRLSSLSRGYRNDETLEADRLEIQQTLSKELNLKL
RMLDDEWKEVRDELNLDLSAAKGDVAKCEYELDAIEDQHGAFLDANIEQAKADLDMLPNW
RADMENLSERHKLQTEKHQDIEAAYNARRSKIGEQLNRELEGLHAEQDKQREARDKQREV
ARADLDALEAQWRSQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLSLAIFDER
IHRADEEQESCNAKVERLTGEERKLRAKRDQANEALRIASLRVNERQTALDELHHMLFPQ
SHTLLEFLRKEAQGWEQSLGKVIAPELLHRTDLHPTVTGESDTVFGVHLDLKAIDVPEYA
ASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRDDLR
RLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQLWLEEQKEQALEARMEK
QAYWQEVIGALDNQLGQIKATIDARRESAKAEQKACETWYKNELKSRGVDEDNILKLKQQ
IRELETKISRAEQRRSEVLRFDDWYQHTWLIRKPKLQTQLSDVKRAASEIDQQLKAKTQE
VKTRRQQLETERKASDAAQIEASENLTKLRAVMRKLAELKLPANNEEAQGSLGERLRQGE
DLLLKRDYLMGSVKQYVEHFDSVIASKSGSGLAETWERAREESSFINDKGIRLLDYRKLV
PQLEQLLNVMVPQSIMALREQGRIFGVDLTAFYDVLADIDRRIASQSARITREVGEELFL
DGVSESAVRIRSKISELEFWPELEQFVKAFKQWKADGFNGLPDEEYTNSMRRALDIIGRA
ALTGGIAKLLEIELRLKEGNSDLIIRTDRQLNESSSHGMAYLILCKFLLAFTRLLRGRAD
VTIHWPIDELGTLHHTNVKKIFDACGNNNISVLGAFPNPESEVLNLFENRYIINKQTKKL
QVVKPKANPIADMLSKRLSKEAI