Protein Info for Shewana3_0614 in Shewanella sp. ANA-3

Annotation: ATPase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 162 to 180 (19 residues), see Phobius details PF14501: HATPase_c_5" amino acids 340 to 437 (98 residues), 33 bits, see alignment E=4.9e-12 PF02518: HATPase_c" amino acids 345 to 428 (84 residues), 60 bits, see alignment E=2.9e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_0614)

Predicted SEED Role

"Sensor protein PhoQ (EC 2.7.13.3)" in subsystem Lipid A modifications (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KST4 at UniProt or InterPro

Protein Sequence (442 amino acids)

>Shewana3_0614 ATPase domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MISIRTKLSLWLTGLLVLGTVIGLILFESMLRQAFHDSIINRLEEDLEHIMLATHINNGE
IHIDQSQLSSFYRPAYSGRYFQLNLPNEVIRSRSLWDMQLDIEPLAPNQTRVWQAKGPKN
NDMQLLSLGLNSSSANVTATLTVAQDLSIGRRVFSEVYGTKLGINLAMLVAMIAGIFLIL
RQSFKPVKQIQHALSRLQEGEINALELNNIPPEVQPLAKTYNELLEYTAKQIERSRNNLG
NLSHGLKTPLAVMQQQVEALGLKDPDTAMALQQQLDAIHKMVERKLAAARITGDMLPAAQ
LVVPRDLHSLANTLNKVHRSKSIDCDFELDPSIQRLPIHREDGMELLGNLLDNAFKWAGS
QVTVKLWKEQNKLCLSIDDDGPGVADDELDKLTQRGTRLDESVMGHGLGLSIVKEIAEQY
GIELKFKHSSHLSGLSIELVFS