Protein Info for Shewana3_0499 in Shewanella sp. ANA-3

Annotation: transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 124 to 144 (21 residues), see Phobius details PF00486: Trans_reg_C" amino acids 23 to 96 (74 residues), 50 bits, see alignment E=1.3e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to she:Shewmr4_0498)

Predicted SEED Role

"Transcriptional activator ToxR" in subsystem Cholera toxin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KSH0 at UniProt or InterPro

Protein Sequence (427 amino acids)

>Shewana3_0499 transcriptional regulator (RefSeq) (Shewanella sp. ANA-3)
MHKITSYLMLDEQAKELVDHVHGTQIGLTFSETAVLVLLLSAPNAIFTKEELLQVGWPER
VVAPTSLTQCISTLRKKLEPYTEVQLKTVARRGYQLHVSEQSHVKMLAINDADAIRDAIV
GVSAWTKLAGIVMLGLILISVWYWSDHHAVVKQVAKWNADKYISLNIGGTLGTAQVLYID
DEEHLHPSWWQKHLAPEGNHISGLPYFSAFAATDGKNYSMAICPSLDAKDCNGKGIINIT
SIDATPAGLNMAEFIPLSKTMEERIRYNRIVLPIDDKGAGELLEHNYHADIYFPVAGELL
VRTDLSMSLVYEGENRGKFYSTSCITDQDCLTTPIKYTIRGEFEQYQTQIDDLNVDVFHV
KVSQKELTKPDEVSGSAMQFYRAIRKHDIRDEDLFYYRVYQNKGTAVWIVPQMGQLLAWT
QYTQVKL