Protein Info for Shewana3_0031 in Shewanella sp. ANA-3

Annotation: TrkH family potassium uptake protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 37 to 58 (22 residues), see Phobius details amino acids 70 to 93 (24 residues), see Phobius details amino acids 132 to 154 (23 residues), see Phobius details amino acids 182 to 205 (24 residues), see Phobius details amino acids 234 to 253 (20 residues), see Phobius details amino acids 271 to 288 (18 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details amino acids 453 to 474 (22 residues), see Phobius details PF02386: TrkH" amino acids 41 to 478 (438 residues), 202.5 bits, see alignment E=5.1e-64 TIGR00933: potassium uptake protein, TrkH family" amino acids 85 to 463 (379 residues), 334.9 bits, see alignment E=3.6e-104

Best Hits

KEGG orthology group: K03498, trk system potassium uptake protein TrkH (inferred from 100% identity to shm:Shewmr7_0023)

Predicted SEED Role

"Potassium uptake protein TrkH" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KR57 at UniProt or InterPro

Protein Sequence (480 amino acids)

>Shewana3_0031 TrkH family potassium uptake protein (RefSeq) (Shewanella sp. ANA-3)
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQS
KTINLNIRDMFLLTSLTWLIVSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLD
TMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLFRTESSDWSDKAVPRTQNMAK
HLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALR
LSSFNVVSVVTTTGYGLTDYGAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIM
REQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMFVIVGLSVILVLTGLDPMTSF
TGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY