Protein Info for Shewana3_4386 in Shewanella sp. ANA-3

Annotation: outer membrane efflux protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF02321: OEP" amino acids 44 to 221 (178 residues), 32.5 bits, see alignment E=3.7e-12 amino acids 252 to 422 (171 residues), 32.1 bits, see alignment E=5.1e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_4386)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L3G8 at UniProt or InterPro

Protein Sequence (427 amino acids)

>Shewana3_4386 outer membrane efflux protein (RefSeq) (Shewanella sp. ANA-3)
MRDLLFNVRTKKPIGYRFSSIVLGMCLVFPAVAVSNEAPQTLTLADAVTLTLLQHPELQI
FNSQQRVMEGRIQQASVGERPEIGLMIEDALGTGEHSALKSMQSTLSFSWLLQQDLIDSR
VNTAKTEATQLDIEKQIKALDLSSQVAKHFIDLLVKQERLKLNLIAEKQAKEVVKTVAKR
VQAGKSSAVETQLAKAELIRRGLAVEDIEHELKASQYQLASQWGKPKASYRFNGNLLDMP
AVPSVDSQLNLLKKHPRFQQFATAQRIAQSQMELARIEAKPQWQVTAGVRRYEASDDFGL
VAGISIPWGSSDRNAGTIAALQAQQDVLANEQNALMQAQDAQLYVLLQEMAHSAHVIDTV
RSDIVPTLEKALSEASNAFDKGLLSYNQYNDVYRELLSAQYQLLDAFESLHLQHIEIQRL
TGTSISQ