Protein Info for Sama_3540 in Shewanella amazonensis SB2B

Annotation: penicillin amidase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 768 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01804: Penicil_amidase" amino acids 43 to 754 (712 residues), 428.4 bits, see alignment E=4.1e-132

Best Hits

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 100% identity to saz:Sama_3540)

Predicted SEED Role

"Family S45 unassigned peptidase (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SBI6 at UniProt or InterPro

Protein Sequence (768 amino acids)

>Sama_3540 penicillin amidase (RefSeq) (Shewanella amazonensis SB2B)
MLKAIKWALLLVFVVCASLYFAFRASLPELSGNTIAPGLEQAVDIERDTLGTAIIRAQSR
RDAAFGLGYAHGQDRFFQMDLLRRNSAGELAELFGDGALTLDERHRFHQFRKRARALLSR
LPAKDRAVLEAYSLGVNQALSQQTLPSFEYLLSGGEITPWQPEDSLLTIFSMYLDLQGNT
VERELVLERIKQLYGNEMLAFVSQNDPIQAALDGSTLPTQAMVAPTLSATALDRAQQSPI
GSELDAFVKGSNNWAVTGQLTQSGHAMLSDDMHLGLAVPIIWYRAQLNYRHQGGETGERD
IQVTGVSLPGAPVIVVGTNGRIAWGFTNGYIDTADWIELDGNEETEIVTEQLKSKGTGKE
MALKLSRFGPVKRLGDKDYALSWVAHGDFAINLNLMHLETATHVDEGLKLTRHTGIPVQN
MLIVDEAGNAAWRLTGAISARDNPTQTAQSADGWQADRWAVPAEDVPVVSNPANQRLWSA
NSRVLSVSDTQRFGDGGYAIASRAAQIRDTLQTKDSFDERDFLAMQLDNRALFLAPWHQL
LTDTLEKQQDEFADDLKALASWGGCACSDSVGYPLVNSFRIRVMDSLFAPLQTRLAEEGL
SLSKIKGNLEVSVWQLLRQQPESWLPEKMADWDSYLLQIYRHNRAELLSRHSQAGKLADL
NWGKVNALKIQHPFSKQIPLLAPLLDMPQVPGFGGHFEPAVQSSGFGASQRLIVQPGRES
NGILMVPGGQSGHPLSPYYRSGFDDYANHRPTPLLPGEVKHMLRLSPQ