Protein Info for Sama_3534 in Shewanella amazonensis SB2B

Annotation: response regulator receiver protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 PF00072: Response_reg" amino acids 3 to 111 (109 residues), 87.5 bits, see alignment E=7.2e-29 PF00486: Trans_reg_C" amino acids 146 to 221 (76 residues), 95.4 bits, see alignment E=1.7e-31

Best Hits

Swiss-Prot: 43% identical to CUSR_ECO57: Transcriptional regulatory protein CusR (cusR) from Escherichia coli O157:H7

KEGG orthology group: K02483, two-component system, OmpR family, response regulator (inferred from 100% identity to saz:Sama_3534)

MetaCyc: 36% identical to DNA-binding transcriptional dual regulator CpxR (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SBI0 at UniProt or InterPro

Protein Sequence (225 amino acids)

>Sama_3534 response regulator receiver protein (RefSeq) (Shewanella amazonensis SB2B)
MKILLVEDDNTTSEYIVKGFSEQGHNIEAAADGHQGLLLATSNQYDLIILDRMLPGLDGL
ALLAALRANANQTPVLILSALSNVDERVKGLRSGGDDYMTKPFAFSELLVRAEILVSRGQ
TAPVQTHLQAGPLEMELLTRNVTLDGHELMLQPKEFQLLKYLMEHPNQVISRTLLFEAVW
DYHFDPRTNVIDVHIAKLRRKFEELGYGELIETVRGAGYRLRQRH