Protein Info for Sama_3479 in Shewanella amazonensis SB2B

Annotation: aromatic amino acid transport protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 45 to 67 (23 residues), see Phobius details amino acids 93 to 111 (19 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 227 to 250 (24 residues), see Phobius details amino acids 262 to 281 (20 residues), see Phobius details amino acids 289 to 312 (24 residues), see Phobius details amino acids 347 to 371 (25 residues), see Phobius details amino acids 391 to 411 (21 residues), see Phobius details PF03222: Trp_Tyr_perm" amino acids 13 to 406 (394 residues), 459 bits, see alignment E=7.5e-142 TIGR00837: aromatic amino acid transport protein" amino acids 19 to 399 (381 residues), 456.7 bits, see alignment E=3.9e-141

Best Hits

Swiss-Prot: 58% identical to MTR_PSEAB: Tryptophan-specific transport protein (mtr) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: K03835, tryptophan-specific transport protein (inferred from 100% identity to saz:Sama_3479)

MetaCyc: 56% identical to tryptophan:H+ symporter Mtr (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-142; TRANS-RXN-76

Predicted SEED Role

"Tryptophan-specific transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SBC5 at UniProt or InterPro

Protein Sequence (418 amino acids)

>Sama_3479 aromatic amino acid transport protein (RefSeq) (Shewanella amazonensis SB2B)
MANHMNAARHPVKTPSLLGGAMIIAGTTVGAGMFSLPVVGAGMWFGYSLLLMVAIWLCML
LSGLLLLETNLRFEPGASFDTLTRDSLGRFGRIVNGLSIAFVLYILTYAYISGGGSIVNH
SLSGMGISLPQSVAGLVFAAVLAAIVMISTKAVDRITTIMLGGMIMTFFLAVGNLLIEVQ
PSNLFSPDGEARFAPFLWAAIPFGLASFGYHGNVPSLVKYYGKNPSVIIKAICIGTFIAL
VIYVCWLLAAMGNLPRSQFSDIIAQGGNMGVLVSALSEVMANDWLGKMLTLFANLAVASS
FLGVTLGLFDYLADLFGFADDAKGRFKTAAVTFLPPTLLGLLFPDGFLVAIGFAALAATV
WTLLVPGVMALKLRKQQPDYPGFRVPGGAGVIYLVISFGILTAACHLLAMAELLPVYR