Protein Info for Sama_3322 in Shewanella amazonensis SB2B

Annotation: serine/threonine protein kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 PF01636: APH" amino acids 30 to 262 (233 residues), 124.1 bits, see alignment E=4.2e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3322)

Predicted SEED Role

"YihE protein, a ser/thr kinase implicated in LPS synthesis and Cpx signalling"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAW8 at UniProt or InterPro

Protein Sequence (325 amino acids)

>Sama_3322 serine/threonine protein kinase (RefSeq) (Shewanella amazonensis SB2B)
MSAAFHFHTLTPDTILDAIESVGVYPETGLTPLNSFENRVYQFRCDRANRYVAKFYRPQR
WTDKQILEEHAFAFELAEAEVPLAAPVVIEGQSLFHFEDFRFALFPSIGGRQFEMDNLDQ
LDAVGHFIGRLHQVGKAGHFSERETLSSAMARDALQVLLASPHVPHSLMADFAAAGQALV
SAIESAWIKTDILRLHGDLHPGNILWTPDGPGFVDLDDARSGPAVQDLWMMLAGDDNERR
MQLDTLLGAYEEFCEFDTRELALIEPLRGLRMLSHMAWISRRWDDPAFPMYFPWFAEDAY
WQRQIRDMQAQVAQIAEPPLSLQPF