Protein Info for Sama_3298 in Shewanella amazonensis SB2B

Annotation: sensory box protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1494 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 783 to 800 (18 residues), see Phobius details PF07494: Reg_prop" amino acids 89 to 111 (23 residues), 17.9 bits, see alignment (E = 1.2e-06) amino acids 357 to 376 (20 residues), 16.8 bits, see alignment (E = 2.7e-06) amino acids 538 to 561 (24 residues), 17.1 bits, see alignment (E = 2.1e-06) amino acids 583 to 605 (23 residues), 18.2 bits, see alignment (E = 9.6e-07) PF07495: Y_Y_Y" amino acids 713 to 755 (43 residues), 37.9 bits, see alignment (E = 5.9e-13) TIGR00229: PAS domain S-box protein" amino acids 852 to 940 (89 residues), 40.2 bits, see alignment 3.5e-14 amino acids 945 to 1062 (118 residues), 53.3 bits, see alignment E=3.1e-18 PF08447: PAS_3" amino acids 853 to 927 (75 residues), 65 bits, see alignment 2.8e-21 amino acids 964 to 1047 (84 residues), 27.3 bits, see alignment 1.6e-09 PF00989: PAS" amino acids 946 to 1052 (107 residues), 32.9 bits, see alignment 2.6e-11 PF08448: PAS_4" amino acids 948 to 1056 (109 residues), 24.4 bits, see alignment 1.3e-08 PF13426: PAS_9" amino acids 952 to 1054 (103 residues), 40.8 bits, see alignment 1.1e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 1065 to 1225 (161 residues), 145.4 bits, see alignment E=1.3e-46 PF00990: GGDEF" amino acids 1066 to 1223 (158 residues), 174.2 bits, see alignment E=8.6e-55 PF00563: EAL" amino acids 1245 to 1477 (233 residues), 237.9 bits, see alignment E=4.7e-74

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3298)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAU4 at UniProt or InterPro

Protein Sequence (1494 amino acids)

>Sama_3298 sensory box protein (RefSeq) (Shewanella amazonensis SB2B)
MFRALFCALLSLILLFGTVPASAEHGSYHYHNTLEFQHFSSSDGLNQNTITRLYTDKAGM
LWAGSQDGLHYFNGQEFGVFLPDPSNTNSLSEGYITDIVQDPEGLLWVSTYTQGLNRLDL
QTGKFTRYGEADGLSELRVTRLAVIGDSLWIGTERGLFAMQRKSGQIRPIPLGNALTPKI
TSLGNIEDEYLLVGTQAHGTYAISSNNIVKLKLPSTSPVNQIHSIGNVAYLAIGKELWQY
EMDTHSAKILWQSEPQGFFHGDIRDFTLASAEEIWAIAPGAGLIELEKTDRWRARYHRND
SRSFRDISDNNLMSVLLDPNGVLWLGGSYSGLDKINIRRQYFDHLFDNSVALPKQINMVR
AIYQTREGVVWIGTEGAGIKTLKPNEDNYQYHTHLFADALNLVPEAISLVVRDIIQDKEG
SLWFASNYGLGHLATSGAFRLLHPPEHDGQGRTLALDKHDTLWVAFDEGLFYMPISGTEL
KRFPLDETLGDKLAVRQILGLEFIDDWLWIGTLDGLIRLNPNTNDIQVFTHDPANSSSLG
NNRIRDIYSAANGDVWVGTHGGISILRQEQDGWQIRHLTSNEGVPSDTIYAILEDKQGQF
WFSSNAGISRYTPGEDSIITFNKFEGLQEQEYNGGVKFVGQDGYFWFGGINGITRFLPEQ
IPKSRQEPPLALTSYSLGGKRTRILDLTTPPSVEMNFEDKVVSFEVTSLDFSYPGVDRFA
YYLQGFDSQWHSAQAQAQITYTNLSPGNYLLRVRHGLAANPLGYQILTVPLTVVAPWYRT
PPAYVLYTLTLVAILGWFWRERRVKRRQRREFETSIRTSEERLKLALWASGDGMWDWDIP
SGQVFRTRMHPHTEQQLNGPVLLDRIHPEDKPRVLHAIEQHIDGSRAFYEAEYRIENKPG
HWIWITDRGKVVERDKQGKPVRMVGTHKDITSRKNAENELRLSAQVLASMNEAVVVGGLD
YRIASVNPAFSLITGFNPEQVQGKHFLFLTHDRKQRHIYEAIEQQLLRNKHWAGELKIRT
RDQRAILIWLEINQVLDSKAEASHFVAVFTDITDRKKAEEDLRLLASYDPLTNLPNRTLF
QDRLDHALAQAHRTGNMVALLFLDLDRFKHINDSMGHHIGDLLLKAVAHRLQNCVREGDT
VARLGGDEFTIILEGVAKTKAATVIAEKLIRAFQTPFILEDQALNISPSIGISLYPMDAS
DSTSLVKYADTAMYHAKSLGRNNFQFYTLRLNEYAMRHVQLEAGIKQAIVRQELSLVFQP
KFRVSDGSITGFEALLRWNSKELGPISPAEFIPLAEEIGIINQLGHWVVNEACRHMAQFA
AAGFDDLHVAVNLSARQLKADILSTIEVALAVAGLPAKCLELELTESMIMKSPQESVAVL
QRLKALGVSLAVDDFGTGYSSLAYLKRFPLDTLKIDREFVRDISTDPDDAAITGAIIALA
HSLELNVVAEGVENEAQLEHLRKHGCDQVQGFLLGKPMAARDAMALLKSRTLNT