Protein Info for Sama_3265 in Shewanella amazonensis SB2B

Annotation: GGDEF domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 862 PF01590: GAF" amino acids 115 to 200 (86 residues), 26.9 bits, see alignment E=1.6e-09 amino acids 263 to 403 (141 residues), 32.9 bits, see alignment E=2.1e-11 PF13185: GAF_2" amino acids 261 to 404 (144 residues), 43.5 bits, see alignment E=9.5e-15 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 446 to 610 (165 residues), 138.6 bits, see alignment E=8.2e-45 PF00990: GGDEF" amino acids 448 to 605 (158 residues), 172.4 bits, see alignment E=1.7e-54 PF00563: EAL" amino acids 629 to 848 (220 residues), 89.9 bits, see alignment E=4.2e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3265)

Predicted SEED Role

"GAF domain/GGDEF domain/EAL domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAR1 at UniProt or InterPro

Protein Sequence (862 amino acids)

>Sama_3265 GGDEF domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MFRDTGFKDEANSPSGGSIERLLKRVDRLRRLAGKYKRAEIIRDALLQITHIATEVNSPE
DFYAGVHLHLKSLIAADNFFIATYNHRTERLEIPFFADEMDPHPAQMYPDRDIHSILMRG
ITGYVFRCGETMLCNEADFERLVAEEAIENLGSASHQWLGVPIRYQERTTGVLVVQTYDP
NVNYGLTEIELMEFISHHISGVMERLRHQEQLEQSIDQRTKELSEAYDKLKLEVYERRRA
ERLQKSLFEIAELSASGLEQEDFYSRLHNILSHLIPASNCYIALLDDTNQQLHFPFYVSQ
LGTEPPSRRPLTDGLTEYLLSRRRPLLLDQKDIQDLVKKGEIYVNTPNLNNTQKMHQWIG
VPLFIGDEVRGALTIYSLSMTQNYQIRDLELLTFVSQHIGTAIERKQHAEFMKKSYERLE
SKVAERTRELELEIQRRREVEQKLIHDAKHDALTGLPNRSMFTERLGQAVRHVRRHGRDQ
FALLFIDLDRFKQINDTLGHLEGDRFLIETARRLSHCIRENDTLGRLGGDEFVVLLDQIN
TPKDAEEVAERILSQLSEPFQLGDALFQSGASIGIAISGRSQQDTPESMLRDADAAMYQA
KSRGKGCYVVYDSKRREEHQAELHDEALLRDALARDELYLKILPVESLSTGEPLAYRLSL
GWRPSKGGELAEDTILSIAERSNLILELDRCLLRHLKRPLPLELNDAELHLCLSSAHLKH
KHALRGLKNMVRELNLDPAKLWLFFDERALVQDTQGHIAGFEALGKLGVSFGLSGYGNGY
SSLKSLTLMPIKALRLAPTTDRLGSEKVRLLTASAMAASSLGLTVIASGTECSLTRQSLV
QAGIDHIQQLQPLHQAQSSVCA