Protein Info for Sama_3166 in Shewanella amazonensis SB2B

Annotation: amino acid carrier protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 459 transmembrane" amino acids 15 to 38 (24 residues), see Phobius details amino acids 71 to 94 (24 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 187 to 205 (19 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 243 to 270 (28 residues), see Phobius details amino acids 306 to 332 (27 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 394 to 414 (21 residues), see Phobius details amino acids 420 to 438 (19 residues), see Phobius details TIGR00835: amino acid carrier protein" amino acids 16 to 444 (429 residues), 498.2 bits, see alignment E=9.4e-154 PF01235: Na_Ala_symp" amino acids 60 to 451 (392 residues), 470.6 bits, see alignment E=2.6e-145

Best Hits

Swiss-Prot: 50% identical to Y883_HAEIN: Uncharacterized transporter HI_0883 (HI_0883) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03310, alanine or glycine:cation symporter, AGCS family (inferred from 100% identity to saz:Sama_3166)

Predicted SEED Role

"Probable sodium:alanine symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAG2 at UniProt or InterPro

Protein Sequence (459 amino acids)

>Sama_3166 amino acid carrier protein (RefSeq) (Shewanella amazonensis SB2B)
MEAVTELVKSLNSLVWGIPMLVMILGVGLYLSLGLKLLPILKLGKGFRLLWSGRTPGQGK
EVKGDVSPFNALMTSLSATIGTGNIAGVATAIFVGGPGALFWMWCTALVGMATKYSEAVL
AVRYREVDEKGNYIGGPMYYIKNGLGSKWTWLGTAFALFGSFAGFGIGNTVQANSVASAL
TSNFGVPAWVSGVVMMVLVGLVLMGGIKRIAIVAGKLVPLMTIFYITAGIAVLVVYASEI
PAALSLIISSAFSPVAAQGGFAGAAVMVAIQMGVARGVFSNEAGLGSAPIAHAAAQTKSP
VTQGLVGMLGTFIDTIIVCSITGLAIVVSGAWTSGENGAALTSYAFSHALPIGDYIVAVA
LAIFAFTTILGWSVYSEKCVQYLLGVKAVMPFRLIWTLVVPLGAMGSLDFVWLLADTLNA
MMAIPNLIALALLSPVVFKLTREFFSSRDEASTKSVEAE