Protein Info for Sama_3111 in Shewanella amazonensis SB2B

Annotation: response regulator receiver protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 PF00072: Response_reg" amino acids 8 to 118 (111 residues), 99.6 bits, see alignment E=1.8e-32 PF13487: HD_5" amino acids 145 to 305 (161 residues), 110.4 bits, see alignment E=1.3e-35 PF01966: HD" amino acids 154 to 275 (122 residues), 65.2 bits, see alignment E=1e-21

Best Hits

KEGG orthology group: K07814, putative two-component system response regulator (inferred from 100% identity to saz:Sama_3111)

Predicted SEED Role

"Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAA7 at UniProt or InterPro

Protein Sequence (328 amino acids)

>Sama_3111 response regulator receiver protein (RefSeq) (Shewanella amazonensis SB2B)
MQDLKPLILVVDDEAANLRVLKQILQDEYQLSFAKSGQEALRLVGQKRPDLILLDIMMPD
MTGLDLCKLLKANPQSAGIPVIFVTALNDEADEATGFAAGAVDYITKPVSSAIVRARVRT
HLSLVQAEELKVTRLKIIQRLGRAAEFKDNETGMHVMRMSHYAKVLARAYGLGESHADML
LHAAPMHDIGKIGIADHILLKPGKLTEEEFEVMKTHPQIGADIIGEDDSLLMQMARTVAL
THHEKWDGSGYPRGIAGEAIPVEGRIVAIADVFDALTSDRPYKKAWSIEDTLRLMREQKG
RHFEPLLVELLEQNLDKILDIKQTFVDE