Protein Info for Sama_3110 in Shewanella amazonensis SB2B

Annotation: putative integral membrane sensor protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1141 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 58 to 82 (25 residues), see Phobius details amino acids 94 to 111 (18 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details amino acids 188 to 211 (24 residues), see Phobius details amino acids 233 to 257 (25 residues), see Phobius details PF03707: MHYT" amino acids 69 to 125 (57 residues), 64.9 bits, see alignment 2.7e-21 amino acids 132 to 177 (46 residues), 45 bits, see alignment (E = 4.4e-15) amino acids 200 to 257 (58 residues), 25.5 bits, see alignment 5.4e-09 TIGR00229: PAS domain S-box protein" amino acids 268 to 394 (127 residues), 87.1 bits, see alignment E=5.1e-29 amino acids 395 to 522 (128 residues), 41.8 bits, see alignment E=5.6e-15 PF00989: PAS" amino acids 272 to 383 (112 residues), 54.6 bits, see alignment E=5.4e-18 PF13188: PAS_8" amino acids 272 to 322 (51 residues), 25.9 bits, see alignment (E = 3.4e-09) PF08448: PAS_4" amino acids 281 to 342 (62 residues), 26.6 bits, see alignment 3.1e-09 PF13426: PAS_9" amino acids 282 to 385 (104 residues), 37.7 bits, see alignment E=1.1e-12 amino acids 418 to 514 (97 residues), 20.6 bits, see alignment E=2.3e-07 PF08447: PAS_3" amino acids 424 to 508 (85 residues), 52.1 bits, see alignment 3.3e-17 PF00512: HisKA" amino acids 536 to 600 (65 residues), 65.8 bits, see alignment 1.5e-21 PF02518: HATPase_c" amino acids 648 to 758 (111 residues), 108.6 bits, see alignment E=1.2e-34 PF00072: Response_reg" amino acids 779 to 894 (116 residues), 71.1 bits, see alignment E=4.4e-23 PF01627: Hpt" amino acids 937 to 1001 (65 residues), 36.2 bits, see alignment 3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_3110)

Predicted SEED Role

"Related to two-component system sensory/regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SAA6 at UniProt or InterPro

Protein Sequence (1141 amino acids)

>Sama_3110 putative integral membrane sensor protein (RefSeq) (Shewanella amazonensis SB2B)
MLNWIVTQFNIPEQSTLIYGNYSVPMVITSVLIAIFASFMALHVAYQAGLTRSSARKHIL
LFIGSLALGVGIWSMHFVGMLAFDLCTPVQYGKTLTLVSMLPGIAASWVALHHIHRHTKG
LKPLIIAGILVGAGIGTMHYSGMAAMEMAPSLRYSLPMFGLSIVVAVSLAMLSLWVRCGL
ISRGSIPLWCANLLASIVMGSAITGMHYTGMAAARFVKPPGLELSPQPPEMSFYLALGVT
TATLVMTSLVLGLSLIYKYKDISLRASESKRRVQAIMETAIDGIVTIDSHGIITDVNQAT
EKLLGWRADELIGQNVKILMPDPFHSEHDGYLARYLATGEARIIGKGREVEAIHKNGHKI
AIRLGIGHVKMAEDDFFVAFISDIRQRLSMEMALRENEQKFRSLIGNIPGIAYRCKNDEQ
WSMIFISNAVEKITGYPASDFMLPSPKRSFSDLFHPDDLEHINNAVPPVGAFNLEYRILH
RNGDIRWMMEYGNHVRDQQSGEMYLDGFIMDITERRQMEQELLEAKDIAEAAATARAAFL
ANMSHEIRTPMNAIIGFSDILLESQFEPEKHRHLKTINHAAKSLLHLLNDVLDSAKLDKG
KLELEVRDFSLVQELDEVISTLWLQARRKGLQLTMEVSPKLLPCYAGSPERIRQVLTNLV
SNAVKFTEKGQVRLTVNPGQGNHVDFVVEDTGIGMSPEQLDKIFDPFTQADASMSRRFGG
TGLGTTISKQLVELMGGHISAGSELGKGSRFCFSLPLNPGVCDELVPLENHVSLPPMTVL
VVDDIAQNLELLSTLLGRDGHRVITESDGQQALARMASEPAIDLVLMDVQMPVMDGLSAS
RARRDKEQREGLTHLPIIALTASVLEDDRTAARQAGMDGFANKPIDYPLLCAEIARVLGL
KHAPIEAATPQSQPGKLIDEKKGMDLWGSRDSYYRQLALFVEEQAEQFERLSSQCHACDW
PALKQTAHGLKGVSANLSLTRLSRNLEKLESLLASHPEQCALFVAPIQQVFAAVKAEVQS
SGYGEAASSGCSALGEPLTAPEKYSAELMPLLTSLRQQAGDNALDEPLLEKLLSFEEGAC
GSQIRAIYQALNDFEFSEAEQRIDALQREISASLSSYQTTAQSANNPAQDAAQSNNGTKE
Q