Protein Info for Sama_3027 in Shewanella amazonensis SB2B

Name: mutL
Annotation: DNA mismatch repair protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 TIGR00585: DNA mismatch repair protein MutL" amino acids 1 to 308 (308 residues), 321.1 bits, see alignment E=5e-100 PF02518: HATPase_c" amino acids 21 to 77 (57 residues), 31.5 bits, see alignment 4.1e-11 PF13589: HATPase_c_3" amino acids 24 to 119 (96 residues), 53.1 bits, see alignment E=7.2e-18 PF01119: DNA_mis_repair" amino acids 213 to 327 (115 residues), 115.8 bits, see alignment E=1.7e-37 PF08676: MutL_C" amino acids 485 to 605 (121 residues), 55.1 bits, see alignment E=1.5e-18

Best Hits

Swiss-Prot: 100% identical to MUTL_SHEAM: DNA mismatch repair protein MutL (mutL) from Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

KEGG orthology group: K03572, DNA mismatch repair protein MutL (inferred from 100% identity to saz:Sama_3027)

Predicted SEED Role

"DNA mismatch repair protein MutL" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1SA23 at UniProt or InterPro

Protein Sequence (650 amino acids)

>Sama_3027 DNA mismatch repair protein (RefSeq) (Shewanella amazonensis SB2B)
MAIQVLPPQLANQIAAGEVVERPASVIKELVENSLDAGATRVDIDIDKGGSKLIRIRDNG
GGIPKAELALALARHATSKVQTLEDLEAILSFGFRGEALASISSVSRLTLTSRTTEQAEA
WQAYAEGSEVAIRVMPAAHPVGTTIEVADLFFNTPARRRFLKSDKTEFTHIDEWLKRIAL
IRSDVHFSLSHNGKPVRQYRCAATDTQYLQRLAQVAGRAFADSAIKVDCQHDGMGLSGYL
QSPALSDMVDCHYFYVNGRLIRDRLVNHAVRQAFGELGTFEQPAFVLSLTLDPHQVDVNV
HPAKHEVRFHQARYVHDFILQVLQSALSQMQDLPLAEELPRAQESPASVREHTAGYAPYT
FNRDAATEAAGVLSSLPDTQRSQRQPEKAASGQRSSVDAGLSQGSSAHRASQTGLGQSGN
AATFETSERHGSGYSGAGQGQRYVRDQLSGQQRQAAQYYAELLHTPEVVSTSGSLQAGLP
MPPLLAGRYWVLAQDEHLRLLSISDAAKALVVQEILSKLPTGLVGQPLLMPVAVAADADW
TMILAERESLLRRLGLELTIRYQQLIIKKVPPYLRDSQLAKLIPEFLEWIKLEVPADEAL
CHWLAQYVTGFDAAPKVWQRIQSLEATERNKILESARDLPWQTWLDEYKH