Protein Info for Sama_2759 in Shewanella amazonensis SB2B

Annotation: transketolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00456: Transketolase_N
  • amino acids 3 to 332 (330 residues), 555.9 bits, E=7.2e-171
• TIGR00232: transketolase
  • amino acids 4 to 662 (659 residues), 1031.3 bits, E=0
• PF02779: Transket_pyr
  • amino acids 353 to 523 (171 residues), 179.1 bits, E=1.6e-56
• PF22613: Transketolase_C_1
  • amino acids 538 to 650 (113 residues), 144.7 bits, E=3.3e-46
• PF02780: Transketolase_C
  • amino acids 539 to 654 (116 residues), 71.7 bits, E=1.3e-23

Best Hits

Swiss-Prot: 84% identical to TKT2_VIBVU: Transketolase 2 (tkt2) from Vibrio vulnificus (strain CMCP6)

KEGG orthology group: K00615, transketolase [EC: 2.2.1.1] (inferred from 100% identity to saz:Sama_2759)

MetaCyc: 78% identical to transketolase 1 (Escherichia coli K-12 substr. MG1655)
Transketolase. [EC: 2.2.1.1]; 2.2.1.1 [EC: 2.2.1.1]

Predicted SEED Role

"Transketolase (EC 2.2.1.1)" in subsystem Calvin-Benson cycle or Pentose phosphate pathway (EC 2.2.1.1)

MetaCyc Pathways

• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (21/26 steps found)
• pentose phosphate pathway (8/8 steps found)
• Bifidobacterium shunt (13/15 steps found)
• Rubisco shunt (9/10 steps found)
• superpathway of glucose and xylose degradation (14/17 steps found)
• Calvin-Benson-Bassham cycle (11/13 steps found)
• pentose phosphate pathway (non-oxidative branch) I (5/5 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (10/12 steps found)
• ethene biosynthesis V (engineered) (19/25 steps found)
• pentose phosphate pathway (partial) (3/3 steps found)
• pentose phosphate pathway (non-oxidative branch) II (5/6 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (20/27 steps found)
• oxygenic photosynthesis (12/17 steps found)
• formaldehyde assimilation II (assimilatory RuMP Cycle) (6/9 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of ansamycins
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Carbon fixation in photosynthetic organisms
• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.1

Sequence Analysis Tools

See A1S9A5 at UniProt or InterPro

Protein Sequence (663 amino acids)

>Sama_2759 transketolase (RefSeq) (Shewanella amazonensis SB2B)
MSRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFI
LSNGHGSMLHYSLLHLAGYDLSIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGIT
NGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAF
WDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLIC
CKTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIA
SEKAWDEKFAAYAAAYPELAAEYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQ
NALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADASGNYLHYGVREFGMTAIINGI
ALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
LRVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGY
VLVDSAAAPELIIIATGSEVELAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVL
PASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPANQLFEMFGFTVDKVVAAAEE
LLG