Protein Info for Sama_2743 in Shewanella amazonensis SB2B

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 50 to 382 (333 residues), 139.9 bits, see alignment E=4.7e-45 PF16576: HlyD_D23" amino acids 75 to 284 (210 residues), 31.3 bits, see alignment E=1.9e-11 PF13533: Biotin_lipoyl_2" amino acids 77 to 124 (48 residues), 23.8 bits, see alignment 4.7e-09 PF13437: HlyD_3" amino acids 187 to 302 (116 residues), 51.6 bits, see alignment E=2.1e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2743)

Predicted SEED Role

"Membrane fusion protein of RND family multidrug efflux pump" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S989 at UniProt or InterPro

Protein Sequence (408 amino acids)

>Sama_2743 hypothetical protein (RefSeq) (Shewanella amazonensis SB2B)
MDKRAPMSTMLRRILPFIILALFILAAMVLMATKEAPEQKAEEANLPIIEVAEVKQETLS
LNLPSYGVVMPRHKTQLVAEVQGRLTSVSPNFVAGGVVKAGDQLAVIEPSDYQADLMQAE
ASLAQATAALNEEIARGEVAKTEFKGYDKGVPPELGLRIPQLKKEQANVKYAEAALARAK
RNLERTVIRAPFDGIVKARGVDLGQYVTLGTKLGELYDTSVAEIRLPLANADLAYLESVD
NPDTEVTLTASLAGREVVWTGDIVRSEGVIDEGNRMVYLVAEIPDPYLRKHKTQGQLPLK
YGTFVNAIIKGRTEDGIVRLDRHLVREGKVPVVRSDNTLELRDVNVVRSDLNYAYIKGSL
KTGERVSLTNTGTLSTGQMVKIRGEETPDSTRDSEAPADERLAQAGDK