Protein Info for Sama_2742 in Shewanella amazonensis SB2B

Annotation: ATP-dependent RNA helicase SrmB (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 PF00270: DEAD" amino acids 25 to 189 (165 residues), 145.5 bits, see alignment E=1.9e-46 PF04851: ResIII" amino acids 36 to 189 (154 residues), 33.7 bits, see alignment E=5e-12 PF00271: Helicase_C" amino acids 232 to 340 (109 residues), 109.5 bits, see alignment E=1.6e-35

Best Hits

KEGG orthology group: K05590, ATP-dependent RNA helicase SrmB [EC: 2.7.7.-] (inferred from 100% identity to saz:Sama_2742)

Predicted SEED Role

"ATP-dependent RNA helicase SrmB" in subsystem ATP-dependent RNA helicases, bacterial

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S988 at UniProt or InterPro

Protein Sequence (613 amino acids)

>Sama_2742 ATP-dependent RNA helicase SrmB (RefSeq) (Shewanella amazonensis SB2B)
MLFEDFQLDPELLESLKAMGHNTPTTIQRMTIPLAMEQRDILARAPTGTGKTASFLLPAL
QHLIDFPRRRPGQPRVLVLTPTRELASQIHRYASHLATNLELDIKLITGGVPYGPQEEML
KSNVDILVATPGRLLEYLDKGHFSAELVEVLVIDEADRMLDMGFGEVVKTIAVEASGRKQ
AMLFSATLEGGGVGSFARELLNEPMFVESEPPRSEKAKIHQWIHLADDKDHKFALLTHLL
KQEEVKRAIVFCKTRDVVASLEGQLQQAGIACAFMRGDMDQKKRFQALGRFTKGEVNVLL
ATDVAARGIDIEDITHVINFDMPRSADTYVHRIGRTGRAGAKGTAISLVEAHDMRILGKV
ERYIEQPLKRRVIEELRPKHKEAKVPTKKKVKAKDAKAKAKNAKPKAAPGRGPATPNAKT
ADSRGGDNVRSGGRASTRRTGTDEKGDGLDKHERRGHDKQERRSHDKGDTGRSQHGARER
TEGQSYASRDGNPRGAKREVGEKTPHSRSDKRHQDTDRQSARGYQSTERSPAQGKARSGS
QSSDRANAEGKPRYNAQGSERNGSKSSDRANAEGKQRYNAQGKDGKRSEKSGDYRSSAPK
GSGGKSRKPSKAD