Protein Info for Sama_2661 in Shewanella amazonensis SB2B

Annotation: amidohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF01979: Amidohydro_1" amino acids 82 to 442 (361 residues), 65.6 bits, see alignment E=5.1e-22 PF07969: Amidohydro_3" amino acids 329 to 439 (111 residues), 35.2 bits, see alignment E=1e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2661)

Predicted SEED Role

"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S907 at UniProt or InterPro

Protein Sequence (484 amino acids)

>Sama_2661 amidohydrolase (RefSeq) (Shewanella amazonensis SB2B)
MPRLNPLARTLCLSFSIALALGLTAHAHAQSLKLTNFQLVDVEQGRLVQGKQLLIEDGRI
VRVAQANEPLGADHTQDLGGQYLLPSLWDMHVHFEGRELVEDNALLLPLYLAYGITAVRE
AASDLAPEVMVWRQQIADGERLGPRIFSAGQKFEGIDSLWSGDMEVGDEAAMGRGMEKLT
AMKVDFIKITENTMAPALYLKTVAEAHRRGFRVSSHIPYGVSVADAARAGLSSIEHVSYV
LRLGHADEAVISASVRDGSVPAKEAAARYRQGFQQQVATEGYKMLATEGVAVTPTLIGGY
QLAHLDTNNHSQDAFLRYLTTAFTDKYRWRIERMGEQTAEQWQARKQRYEAEASQLRHLE
AAGVMLLAGSDSAALNTYVYPAEGLHTELQLWQKAGLSPARILRAATLDGAKFMGLDKDY
GSIAEGKRADLLVLKANPLVDISATLKIHSLVQGGEYHNEAELARWKDNAAAAVQILNTG
RKDI