Protein Info for Sama_2630 in Shewanella amazonensis SB2B

Annotation: lipolytic enzyme, G-D-S-L (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF14606: Lipase_GDSL_3" amino acids 29 to 130 (102 residues), 33 bits, see alignment E=1.1e-11 PF00657: Lipase_GDSL" amino acids 30 to 121 (92 residues), 47.6 bits, see alignment E=3.6e-16 PF13472: Lipase_GDSL_2" amino acids 32 to 183 (152 residues), 81.3 bits, see alignment E=2e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_2630)

Predicted SEED Role

"Acyl-CoA thioesterase I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S8X6 at UniProt or InterPro

Protein Sequence (198 amino acids)

>Sama_2630 lipolytic enzyme, G-D-S-L (RefSeq) (Shewanella amazonensis SB2B)
MRILSVFFILLFLSACGGPRLPFLGENARILAFGDSLTFGIGASDGMDYPAHLSRLCDCD
VINAGVSGETTTEGLARLAELLDETQPDLLILLEGGNDILRNQDKAQLKRNLEAMIREAQ
GRQVPVLLIAVPDRKVFLSPLPLYQELAEQFSLPLLEDTLPQLLSQSAMKSDTVHLNDAG
YQLLAEEIYQLASESGAF