Protein Info for Sama_2439 in Shewanella amazonensis SB2B

Annotation: L-lactate permease, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 30 to 48 (19 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 101 to 120 (20 residues), see Phobius details amino acids 122 to 122 (1 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 155 to 173 (19 residues), see Phobius details amino acids 198 to 225 (28 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 264 to 281 (18 residues), see Phobius details amino acids 319 to 340 (22 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 398 to 416 (19 residues), see Phobius details amino acids 425 to 447 (23 residues), see Phobius details amino acids 449 to 470 (22 residues), see Phobius details amino acids 494 to 516 (23 residues), see Phobius details amino acids 528 to 546 (19 residues), see Phobius details PF02652: Lactate_perm" amino acids 6 to 543 (538 residues), 342.6 bits, see alignment E=2.3e-106

Best Hits

KEGG orthology group: K03303, lactate transporter, LctP family (inferred from 100% identity to saz:Sama_2439)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S8D7 at UniProt or InterPro

Protein Sequence (547 amino acids)

>Sama_2439 L-lactate permease, putative (RefSeq) (Shewanella amazonensis SB2B)
MTFVQLLASLSPVISVMLFLVLLRLPASKAMPISAVVTALAAILVWQMDTQMLAASVVEG
LLSALTPLSIIFGAVFLLNTLKYSGAMDTIRAGFTNISADARVQVIIICWLFGAFIEGSA
GFGTPAAIGAPLLVLLGIPPVAAAVVALIADSASVSFGAIGLPVLFGMEQGLIEGGTSMA
AAQIAEHGGHFSDYARYIAMHMISIDLITGTLIPLVMVTVLTGFFGRKKSFAEGLAIWKF
AIFAGLAFTVPAWIINFIAGPEFPSVIGALLGMAMVIPVARKGWLLPKTSWHDFEESTEN
GNDVPHTEVRFSQLAAWTPYLVMAALLVASRTIAPLKAWLGGFNISWTHLLGTDLKASFA
TLYAPGAFFVLVCLLGFVLFKMRSDAMRNSVTVSLKSMIPTVISLGASVPMVKIFLNSGA
NEAGLASMPVALADMLAGSMGAVWNWMAPVVGIFGAFLSGSATFSNMMFSGLQYSVADNI
GANHALTLALQGIGANAGNMMCVMNVVAAATVVGMAGRESEIIRKTMPVALGYALLAGTI
ATLWGGF