Protein Info for Sama_2233 in Shewanella amazonensis SB2B

Annotation: putative hydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF02811: PHP" amino acids 6 to 80 (75 residues), 31.6 bits, see alignment E=1e-11

Best Hits

Swiss-Prot: 100% identical to Y2233_SHEAM: Probable phosphatase Sama_2233 (Sama_2233) from Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

KEGG orthology group: K04477, putative hydrolase (inferred from 100% identity to saz:Sama_2233)

Predicted SEED Role

"putative histidinol phosphatase and related hydrolases of the PHP family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S7T2 at UniProt or InterPro

Protein Sequence (251 amino acids)

>Sama_2233 putative hydrolase (RefSeq) (Shewanella amazonensis SB2B)
MQFPVDTHSHTVASTHAYSTIHDYLAVAKEKGIRLFATTDHGPAMKDAPHFWHFVNLRVL
PRIWNGVGILRGIEANIMNEKGEIDYFGEYLSELDLVQAGFHEPVFAPADRLTHTRAMIA
TMESGLVDIITHPGNPAYPIDVEAVVGAAKACNVALEINNSSFTASRKGSEENCLAIARM
ATKLDAQLVMGSDAHVAFDLGGFDRSLAIVDAADYPRQRLLNESPMALLHFLQQRGHQHL
DELIRYFRPVL