Protein Info for Sama_2091 in Shewanella amazonensis SB2B

Annotation: prolyl oligopeptidase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 718 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 44 to 440 (397 residues), 399.6 bits, see alignment E=1.5e-123 PF00326: Peptidase_S9" amino acids 499 to 711 (213 residues), 209.1 bits, see alignment E=5.8e-66

Best Hits

Swiss-Prot: 43% identical to PPCF_ELIMR: Prolyl endopeptidase from Elizabethkingia miricola

KEGG orthology group: K01322, prolyl oligopeptidase [EC: 3.4.21.26] (inferred from 100% identity to saz:Sama_2091)

Predicted SEED Role

"Prolyl endopeptidase (EC 3.4.21.26)" (EC 3.4.21.26)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.26

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S7E0 at UniProt or InterPro

Protein Sequence (718 amino acids)

>Sama_2091 prolyl oligopeptidase (RefSeq) (Shewanella amazonensis SB2B)
MTSRISTLSLLTLGFALGLSGCHTKDATVDAPVAAIAYPASQTVAISEQIHGVEVQDPYR
WLEESSPETEDWVKRQQAFGEEYLAAIPNKQVVVDRITELWNFEKVGAPFEHGENRFIFR
NNGLQSQNVLYVSEKGGDERVLLDPNTLSADGTVALSGVSVSGDGKTLAYGVSKSGSDWQ
EWAFIDVATGRKLADSLNWIKFSRAEWAHDNSGVYYSRYDAPAGGDILVDVNYNQKVYFH
RIGDEQAKDTLVYERPDQPEWGFSSTVSDDGNFLLISVSVGTDSRNRFFYKPLKDKSLKV
VELMSELEAEYQFLGNEGPVFYFKTDLDAPRGRIIAVDTRNPAKDNWRTLVPESQDPIAE
VSIISEHLVVSYLHDVLGQLSIYNMDGVKREDVPLPGKGKIAGPYGKASKPYFYYIFNSY
VQPQTIYKYDLNKGTNEVFSAPKVSFNPDDYVSEQVFYTSKDGTRIPMLVSYKKGLKKDG
KNPTLLYAYGGFSISMTPRFSPATIAWLDMGGIYAVPALRGGSEYGEEWHKAGMFGKKQN
VFDDYFAAAEYLISENYTNSSKLGAYGRSNGGLLMGAAVTQRPDLFAAILPAVGVLDMLR
FQKFTIGWAWTAEYGSADNAEDFPYLLAYSPYHNVKAQTYPATMVMTADHDDRVVPLHSF
KFGAMLQAKQQGQAPVIMRIESKAGHGAGKPTAMQIAEFADIYAFLWQNFGLTLPTEL