Protein Info for Sama_1940 in Shewanella amazonensis SB2B

Annotation: ATP-dependent helicase DinG (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 PF00270: DEAD" amino acids 36 to 144 (109 residues), 28.8 bits, see alignment E=9.6e-11 PF13307: Helicase_C_2" amino acids 488 to 647 (160 residues), 154.1 bits, see alignment E=3.7e-49

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 100% identity to saz:Sama_1940)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S6Y9 at UniProt or InterPro

Protein Sequence (665 amino acids)

>Sama_1940 ATP-dependent helicase DinG (RefSeq) (Shewanella amazonensis SB2B)
MSSQSAANNLITRTQAVFDEGGLLSRFIRGYRRREVQQQMAEEVASCLSHTHKLVLEAGT
GVGKTFAYLVPALLSGKQVIVSTGSKNLQEQLFYKDLPALLEMLKLHLPVSILKGRSNYL
CQRLMAAQMEAAFSHDEKLLDDLLKLNQFAQTTEDGDLGNLTGVAEDARAISLVASTQDS
CTGQRCAFYEDCFTRKARARAMNARLIVVNHHLFFADRVLKDTGFAELLPDVDAVIFDEA
HLLPDIAMQYFGAQLSTGSLRRLLDGIERLTEGELGDTQGLKLLPQRARIKLDAWQNCLL
DAGSSDFRQLLKDKTAALAAGELIAELSALEALLLANVGRSEPLDDFAVKLPELKQKLER
FIACDDPGSAYSIDIGERHLMLRISPIDIAKACSELFSEDTAWVFTSATLQVERSLQFFT
RELGLTSAKPVSAKRSQSGAGAKSAVCKEVLLDSPFDYPRQSLLCVPRRLGSVANQDAMV
CQLTEVCLKLIRAAKGRTFILFTSHRMMEAVARSLVGRCHYPLLVQGQGGKQQLLSKFRQ
LGEAVLLGTGSFWEGVDVRGKLLSCVIIDKLPFASPDDSLYKARASRVEARGGDPFLEIS
LPQAVIALKQGAGRLIRDETDRGVLVICDNRLVNRPYGQAFLQSLPPMARTRDLDEACAF
LAAID