Protein Info for Sama_1922 in Shewanella amazonensis SB2B

Updated annotation (from data): yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB)
Rationale: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
Original annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 PF04285: DUF444" amino acids 4 to 421 (418 residues), 633.2 bits, see alignment E=1.2e-194

Best Hits

Swiss-Prot: 86% identical to Y2883_SHEON: UPF0229 protein SO_2883 (SO_2883) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K09786, hypothetical protein (inferred from 100% identity to saz:Sama_1922)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S6X1 at UniProt or InterPro

Protein Sequence (423 amino acids)

>Sama_1922 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) (Shewanella amazonensis SB2B)
MANFIDRRLNAKGKSTVNRQRFINRYKKQIKKAVSDAVTRRSVTDVDKGEQISIPTRDIT
EPMFHQGRGGFRERVHPGNDQFTRGDRIDRPPQGGGGQGSGQGDASDSGDGQDDFVFQIS
KDEYLELLFEDLELPNLQRNRLNKLVEYQVQRAGYTNDGVPANISIVRSLRSSLARRTAM
TAAKKRHLKTLEAELEELENTPGANADRILALKTEIEALRKKIDAVPFIDTFDLRYNNFT
KREVPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLTRTYKNLEVVYIRHHTQAKE
VDEHEFFYSQETGGTIVSSALKLMVEIQKERYPAEEWNIYAAQASDGDNWADDSPTCRQI
LEKQILPTVRYFSYIEITNRAHQTLWREYDSLRQVYDNMAVQHIRQAEDIYPVFRELFKK
QAV