Protein Info for Sama_1888 in Shewanella amazonensis SB2B

Annotation: ribonuclease activity regulator protein RraA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 164 TIGR01935: RraA family" amino acids 6 to 154 (149 residues), 207.4 bits, see alignment E=4.6e-66 PF03737: RraA-like" amino acids 7 to 153 (147 residues), 154.6 bits, see alignment E=1.2e-49

Best Hits

Swiss-Prot: 59% identical to RRAAH_SHEON: Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase (SO_2567) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K02553, regulator of ribonuclease activity A (inferred from 100% identity to saz:Sama_1888)

Predicted SEED Role

"Ribonuclease E inhibitor RraA" in subsystem RNA processing and degradation, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S6T7 at UniProt or InterPro

Protein Sequence (164 amino acids)

>Sama_1888 ribonuclease activity regulator protein RraA (RefSeq) (Shewanella amazonensis SB2B)
MLDLLPDLFDEFAEHLTLVAAPWRQFGAKRIFYGQVVTVSCFEDNSRVKELLATPGMGRV
LVVDGGGSQRKALVGDLIAQSALDNGWAGIVVYGAIRDVGTLATLNIGVQALGSVPIKTE
RRGLGDTGVTLNLVGVTVNPGDWIYADDNGIAVSREALPIIEQD