Protein Info for Sama_1829 in Shewanella amazonensis SB2B

Annotation: putative diguanylate phosphodiesterase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 139 to 158 (20 residues), see Phobius details PF00990: GGDEF" amino acids 224 to 376 (153 residues), 42.1 bits, see alignment E=7.8e-15 PF00563: EAL" amino acids 401 to 629 (229 residues), 181 bits, see alignment E=2.6e-57

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_1829)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S6M8 at UniProt or InterPro

Protein Sequence (646 amino acids)

>Sama_1829 putative diguanylate phosphodiesterase (RefSeq) (Shewanella amazonensis SB2B)
MELAMSLIKTFPIALILLFGSAALWLHQENLGLMQDAGKALETQYRNKTTELASWHGDGQ
ALYQHLQQSITLQFFQYTDGTDGSRNFTTGQLQETPESFLARLFPLEISDTRNLPDGRLM
VKLDTNGPRTLAVSLYSEQLIIIGSLFAASLLLFLALASTLSRKIRYAAEYVKSLTELNF
SPPEQSKLGGELKPLATVFEEARQALKQKIDGLHHENEKLSRAAFQDPITGFGSRARFTR
KLDELAKSQKDLLGSLAMLQATELGTINQLKGRTAGDDYLAKVAGCLRKAGSPFPDAEFY
RISSSDFAVFLPNLVISDAERFLEPLKTLLDEYQSTSAMESIAYTGLVPYKSGVDPVGLL
SLSDAALSIAQTLGANSFHVLEKFTEDQEIGDNRWQVAITEIITQRAVRFFQQPIQPCRS
EVEVYRELFARFFNSEGKVLPTATVIAMAERHGLSQELDKLVVLSAVRMLLDNPNMTGAY
GVNISAVSATDDNFVVWLKDLLTKHRAISNRLVLEINESGLQTNMQGSFRFIREIHSVGT
RVSIERFGMGFTSFKFFREVRPDYIKLDATYSEAIDQDANNKFFVRMMIDIARRIGVRVI
ACGVERQEEKLTLEKLMVDGLQGFYIAKPEPAGSKDLLDEKLTRQS