Protein Info for Sama_1617 in Shewanella amazonensis SB2B

Annotation: asparaginase family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01112: Asparaginase_2
  • amino acids 13 to 323 (311 residues), 395.2 bits, E=9.7e-123

Best Hits

Swiss-Prot: 53% identical to IAAA_ECOLI: Isoaspartyl peptidase (iaaA) from Escherichia coli (strain K12)

KEGG orthology group: K13051, beta-aspartyl-peptidase (threonine type) [EC: 3.4.19.5] (inferred from 100% identity to saz:Sama_1617)

MetaCyc: 53% identical to isoaspartyl dipeptidase proenzyme (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Isoaspartyl aminopeptidase (EC 3.4.19.5) @ Asp-X dipeptidase" (EC 3.4.19.5)

MetaCyc Pathways

• cyanophycin metabolism (2/6 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.4.19.5

Use Curated BLAST to search for 3.4.19.5

Sequence Analysis Tools

See A1S618 at UniProt or InterPro

Protein Sequence (327 amino acids)

>Sama_1617 asparaginase family protein (RefSeq) (Shewanella amazonensis SB2B)
MTPASAQENPFGIAIHGGAGTISKARLTDEQEQAYRDKLEEAVNAGHKILAKGGDSLDAV
KAAINILEDSPLFNAGMGAVYTFDGTHELDASIMDGNTMNAGAVAGVKHIKNPIDLALVV
MNKSDHVMLSGVGAEEFALTQGMPLVPANTFDTDSRYQQLLDAKAKINAAESAAKDFHAS
ATSLDLDYKFGTVGAVALDKNGNLAAGTSTGGMTAKRFGRIGDSPVIGAGTYAENGVCAV
SATGHGEYFIRYHVAADICARMKYQQKNVIQASDEVINQRLVEAGGSGGIIAIDAQGNVA
TPFNTEGMYRASRVNKDAPLIMIWRDK