Protein Info for Sama_1524 in Shewanella amazonensis SB2B

Annotation: CBS domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 PF00027: cNMP_binding" amino acids 57 to 122 (66 residues), 41 bits, see alignment E=3.1e-14 PF00571: CBS" amino acids 155 to 208 (54 residues), 38.5 bits, see alignment 2.4e-13 amino acids 221 to 271 (51 residues), 46.1 bits, see alignment 9.8e-16 PF03445: DUF294" amino acids 298 to 434 (137 residues), 159.3 bits, see alignment E=1.1e-50 PF10335: DUF294_C" amino acids 471 to 614 (144 residues), 151.6 bits, see alignment E=2.7e-48

Best Hits

KEGG orthology group: K07182, CBS domain-containing protein (inferred from 100% identity to saz:Sama_1524)

Predicted SEED Role

"Predicted signal-transduction protein containing cAMP-binding and CBS domains" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S5S5 at UniProt or InterPro

Protein Sequence (618 amino acids)

>Sama_1524 CBS domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MICMDASEIQPLTQFLRQLVPFDSLSDASLLACVRHLSVAYYSKSMGHVPLDESHPRLYI
VRSGAFEVRDEEGELVDRLGEGDFFGFPSLLSGEAISNKVAILEDGLVYQLSPDMFNSLR
QESREFDRFFNRAFAKRLRHQGRFKAKELTTTSRISSLMTGSPLTIDCNHSIRQAAVMMR
DARVSSLLVTDHHKLCGILTDRDLRNRVLAEGFDGTLPVHQAMTRNPVTIGAGALVFEAM
LAMSERNIHHLPVLEGDTPVGVISSTDILRSQGSQPLMLIGEIERQKDVASLISVSKKIP
ELLQSLISADARAEEIGRVLTSVTDALTRRLILLNQQILGQAPMAFCWLAFGSQGRQDQA
ACSDQDNGLLLAGEPDEHAAGYFEALSRAVCSGLDECGYRFCPGDIMAQNPKWRMSLARW
QQVFDNWVKAPEPKALMHASIFFDMRPVFGPQSLFDALQDKVLAGTRDNDIFLAGMAGNS
LTEAPPLGFFRKFVLERDGSEVKGIDLKHKGNALINDIARVYALSAGIKEVNTAKRIRAL
MELGVIGRKDALNLADAHEFIAHMRLANQGVQHRQGQEISNYLKPQQLSSLVRHQLRDAF
KVVHDAQSGLRLKFMRSF