Protein Info for Sama_1494 in Shewanella amazonensis SB2B

Annotation: phosphate acetyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13500: AAA_26
  • amino acids 3 to 229 (227 residues), 153.6 bits, E=9.6e-49
• PF07085: DRTGG
  • amino acids 233 to 344 (112 residues), 102.1 bits, E=2.2e-33
• PF01515: PTA_PTB
  • amino acids 391 to 706 (316 residues), 419.6 bits, E=1.4e-129
• TIGR00651: phosphate acetyltransferase
  • amino acids 406 to 706 (301 residues), 442.5 bits, E=4.4e-137

Best Hits

Swiss-Prot: 66% identical to PTA_VIBCH: Phosphate acetyltransferase (pta) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K13788, phosphate acetyltransferase [EC: 2.3.1.8] (inferred from 100% identity to saz:Sama_1494)

Predicted SEED Role

"Phosphate acetyltransferase (EC 2.3.1.8)" in subsystem Ethanolamine utilization or Fermentations: Lactate or Fermentations: Mixed acid or MLST or Propanediol utilization or Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Threonine anaerobic catabolism gene cluster (EC 2.3.1.8)

MetaCyc Pathways

• mixed acid fermentation (15/16 steps found)
• heterolactic fermentation (15/18 steps found)
• superpathway of L-threonine metabolism (15/18 steps found)
• L-threonine degradation I (6/6 steps found)
• pyruvate fermentation to acetate II (3/3 steps found)
• pyruvate fermentation to acetate IV (3/3 steps found)
• superpathway of acetate utilization and formation (3/3 steps found)
• acetate and ATP formation from acetyl-CoA I (2/2 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (7/9 steps found)
• acetylene degradation (anaerobic) (4/5 steps found)
• ethanolamine utilization (4/5 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (14/19 steps found)
• superpathway of N-acetylneuraminate degradation (16/22 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (3/4 steps found)
• pyruvate fermentation to acetate I (2/3 steps found)
• pyruvate fermentation to acetate VII (2/3 steps found)
• sulfoacetaldehyde degradation I (1/2 steps found)
• (S)-propane-1,2-diol degradation (3/5 steps found)
• pyruvate fermentation to acetate and lactate II (2/4 steps found)
• acetyl-CoA fermentation to butanoate (4/7 steps found)
• superpathway of Clostridium acetobutylicum acidogenic fermentation (5/9 steps found)
• lactate fermentation to acetate, CO₂ and hydrogen (Desulfovibrionales) (4/8 steps found)
• sulfolactate degradation II (1/4 steps found)
• methanogenesis from acetate (2/6 steps found)
• superpathway of sulfolactate degradation (2/6 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (7/13 steps found)
• superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
• superpathway of taurine degradation (1/6 steps found)
• L-lysine fermentation to acetate and butanoate (3/10 steps found)
• gallate degradation III (anaerobic) (3/11 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (7/17 steps found)
• purine nucleobases degradation II (anaerobic) (11/24 steps found)
• superpathway of methanogenesis (2/21 steps found)
• superpathway of L-lysine degradation (8/43 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Pyruvate metabolism
• Taurine and hypotaurine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.8

Sequence Analysis Tools

See A1S5P5 at UniProt or InterPro

Protein Sequence (712 amino acids)

>Sama_1494 phosphate acetyltransferase (RefSeq) (Shewanella amazonensis SB2B)
MSRNIMLVPIGTGVGLTSLSLGMVRALERHGVKVQFFKPISQQRPADSGPERSTTILSKS
PTVNPLEPFDMQHAESLIRTDQTDVLMEQIIARASEIAANTETLIIEGLVPTRSHSFSDD
VNYAIAKALDADVIFIATPGNDTPNALMNRLEIAYNSWGGAKNKRLIGAVINKIGAPVDD
EGRTRPDLSEVFDHQDIQKGDATAMFQLPGKSKLRILGSVPYNLDLVSPRASDLAKHLHA
RILNAGEMNTRRLRKVTFCARSIPNMLSHFRTDSLLVTSGDRSDVIVAACLAAMNGVKIG
ALLLTGSYEPEPEVLKLCEQAFETGLPVFMIDTNTWQTSLNIQRFNHEVPVDDAVRIELV
QEYVASHIDQSWIESVTENSPREHRLSPPAFRYKLTELARAAKKCIVLPEGDEPRTIKAA
SICAERGIARCVLLGKKDDILRIAAAQDVVLGEGVEILDPEDIREQYVEPMLNLRRHKGL
TEVVAREQLEDNMVLATMMLAEDEVDGIVSGAVNTTANTIRPPLQLIKTAPGSSLVSSIF
FMLMPDQVLVYGDCAINPDPNAEQLADIAIQSAESAKAFGIEPRVAMISYSTGNSGTGSD
VDKVREATRIAKEKRPDLVIDGPLQYDAAVMPNVARSKAPDSPVAGKATVFVFPDLNTGN
TTYKAVQRSAELISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQQ