Protein Info for Sama_1426 in Shewanella amazonensis SB2B

Name: sdhB
Annotation: succinate dehydrogenase iron-sulfur subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF13085: Fer2_3" amino acids 5 to 109 (105 residues), 115.4 bits, see alignment E=2.5e-37 TIGR00384: succinate dehydrogenase and fumarate reductase iron-sulfur protein" amino acids 7 to 227 (221 residues), 288.2 bits, see alignment E=1.9e-90 PF13183: Fer4_8" amino acids 143 to 217 (75 residues), 40.9 bits, see alignment E=4.8e-14 PF13534: Fer4_17" amino acids 145 to 218 (74 residues), 39.1 bits, see alignment E=1.8e-13 PF13237: Fer4_10" amino acids 145 to 214 (70 residues), 37.4 bits, see alignment E=3.9e-13

Best Hits

Swiss-Prot: 77% identical to SDHB_SALTY: Succinate dehydrogenase iron-sulfur subunit (sdhB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K00240, succinate dehydrogenase iron-sulfur protein [EC: 1.3.99.1] (inferred from 100% identity to saz:Sama_1426)

MetaCyc: 77% identical to succinate:quinone oxidoreductase, iron-sulfur cluster binding protein (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)" in subsystem Serine-glyoxylate cycle or Succinate dehydrogenase or TCA Cycle (EC 1.3.99.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.1

Use Curated BLAST to search for 1.3.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S5H7 at UniProt or InterPro

Protein Sequence (235 amino acids)

>Sama_1426 succinate dehydrogenase iron-sulfur subunit (RefSeq) (Shewanella amazonensis SB2B)
MKLEFSVYRYNPDVDTKPRMQDYSFDVPDGSDMMVLDALLKLKEIDPTLSFRRSCREGVC
GSDGMNMNGKNGLACITPISTFKGKKIEIRPLPGMPVVRDLVVDLSQFYKQYEKIKPYLI
NDEKKPAREHLQSPEERAHLDGLYECIMCACCSTACPSFWWNPDKFVGPSGLLHAYRFLI
DSRDTATEERLAELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV