Protein Info for Sama_1394 in Shewanella amazonensis SB2B

Annotation: TonB-dependent receptor, plug (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 713 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 50 to 154 (105 residues), 66.4 bits, see alignment E=3.2e-22 PF00593: TonB_dep_Rec" amino acids 245 to 678 (434 residues), 98.1 bits, see alignment E=1.2e-31

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to saz:Sama_1394)

Predicted SEED Role

"Aerobactin siderophore receptor IutA" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S5E5 at UniProt or InterPro

Protein Sequence (713 amino acids)

>Sama_1394 TonB-dependent receptor, plug (RefSeq) (Shewanella amazonensis SB2B)
MKLSPVAIALSPLMALTAAPAFAEVKDTTSPDTIAIERMIVTGSRVPERLDEVPSSVTLI
DSKTLATEMSISSELQNMLATRVPGMSPATGTSSNAGQTLRGRKALILIDGVPQSTPLRN
GSLDIRSIDMNAIERVEVIKGATSIYGNGAAGGIINYITKKPGADGAIGGVLGVSSRFSA
VKFEDSVGSRVEGALNGSVGQLGYLISASRDDYGLQRDAEGDVPGLVYGLSETTTDNLFT
KFHFNFDDEKSLQLTYNYFSSAQDARMVDVTGSVNSGQKTYAIEAGPDTLILGEPQGVDG
NHNLMVKYEDLALFDNTRLAIDAYGQKIENVFFYSLTLANPEQGLDGGQSIIRSEKRGVR
ANFNSDFTLGDTELDLLYGIDYLQDVSSQPLVDGRMWVPEMDMQNLAFYLQAKWLFAEDW
VLKAGVRRDQMAIEVDDYQTLRLCRTATQCSTPVAVKGGELEFDANTYNIGLRYKGSTVF
SPFISFSQGADISDLGLLLRTATVDDLAKIQSQAALIDNYEAGFDGHWEAFSYSAAVFLS
KSELGTRTVLNPASGIYEPVRAPQEIKGIELAASYDVNDELTLGANYSWMEGKDTDQDIY
LDGQAITPPKFAAYLDWATTDNSSVSLTWLHVGDRKRFEPVNGQYSGSQGPVESYSLLNL
AGNYRVDQLLFTLGVENLLNEDYYSARSQAFTFPGYNTKGLGTTVNMGLKWSF