Protein Info for Sama_1259 in Shewanella amazonensis SB2B

Annotation: TPR domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13432: TPR_16" amino acids 54 to 109 (56 residues), 15.8 bits, see alignment 7e-06 amino acids 84 to 143 (60 residues), 19.4 bits, see alignment E=5.3e-07 amino acids 340 to 385 (46 residues), 22.4 bits, see alignment 6e-08 PF13424: TPR_12" amino acids 82 to 142 (61 residues), 30.1 bits, see alignment E=2e-10 PF13181: TPR_8" amino acids 84 to 109 (26 residues), 19.5 bits, see alignment (E = 3.9e-07)

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_1259)

Predicted SEED Role

"TPR domain protein, putative component of TonB system" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S510 at UniProt or InterPro

Protein Sequence (416 amino acids)

>Sama_1259 TPR domain-containing protein (RefSeq) (Shewanella amazonensis SB2B)
MRQVKLASALLLSLTAGALVMPVAQAAEKCPMEKRQSRAVGETVGKKVQKSFEAYTNGQV
DEAIAILLEANAKGDFDKAYVARMLGNFYAEKGKMDTAIKYMKQAVEADVLGGTDHAASM
KLYADLLIQEKKWKEAIAVYYKWMDFACKTDDPVVYRRIGIAYSELKQWDKVLEVADQGL
SHAKEPDKNLYQMKLTAYFEKKQYKNAVKVLETMVPLFQDDKRLWIQLAQFYLLTEDFPR
SLQTYDLSYRNGFLKEDAGSLVRYSQLLASQGSPYRAATIMEKFMKAGVIESNAKHYEQL
AGFFQNSKEIEKAAEYYGKAAEEKKDGKLFLKQGRMLALAEKYSAAVPALEKSLDAGIPN
PGEAHFELALIHLQLKQYKSAYSRAKLAAQDKKTERSAKSYISYIQEKARINNVTL