Protein Info for Sama_1256 in Shewanella amazonensis SB2B

Annotation: MotA/TolQ/ExbB proton channel (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 175 transmembrane" amino acids 22 to 41 (20 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details PF01618: MotA_ExbB" amino acids 62 to 167 (106 residues), 80.1 bits, see alignment E=6.4e-27

Best Hits

KEGG orthology group: K03561, biopolymer transport protein ExbB (inferred from 100% identity to saz:Sama_1256)

Predicted SEED Role

"Ferric siderophore transport system, biopolymer transport protein ExbB" in subsystem Campylobacter Iron Metabolism or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S507 at UniProt or InterPro

Protein Sequence (175 amino acids)

>Sama_1256 MotA/TolQ/ExbB proton channel (RefSeq) (Shewanella amazonensis SB2B)
MMLFLMDVWDSVRGFMATGGDVLWLVAVVLFLMWVLMLERFWYLNWIAPKQHLAIIASWE
AREETTSWYAHRIREAWVSQAKQDMNARMLMIKTLVALCPMIGLLGTVTGMITVFDVMAV
QGTSNARMMAAGISQATMPTMAGMVAALSGVFFSTRLDAKMRISLERLKDSLPHH