Protein Info for Sama_1230 in Shewanella amazonensis SB2B

Annotation: trans-2-enoyl-CoA reductase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 PF12242: Eno-Rase_NADH_b" amino acids 2 to 80 (79 residues), 122.2 bits, see alignment E=9.2e-40 PF12241: Enoyl_reductase" amino acids 82 to 317 (236 residues), 368.8 bits, see alignment E=1.6e-114 PF07055: Eno-Rase_FAD_bd" amino acids 326 to 389 (64 residues), 102.7 bits, see alignment E=1.6e-33

Best Hits

Swiss-Prot: 100% identical to FABV_SHEAM: Enoyl-[acyl-carrier-protein] reductase [NADH] (fabV) from Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)

KEGG orthology group: None (inferred from 100% identity to saz:Sama_1230)

Predicted SEED Role

"Short-chain alcohol dehydrogenase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S4Y1 at UniProt or InterPro

Protein Sequence (400 amino acids)

>Sama_1230 trans-2-enoyl-CoA reductase (RefSeq) (Shewanella amazonensis SB2B)
MIIKPKIRGFICTTTHPVGCEANVLEQINLTKARGPIVNGPKRVLVVGSSSGYGLSSRIA
AAFGSGAATIGVFFEKPGTESKPGTAGWYNSAAFDKFAKAEGLYSKSINGDAFSHEAKAK
AIELIKADLGQIDMVVYSLASPVRKLPDSGELVRSSLKPIGQPYSSTAVDTNKDTIIEAS
VEPATEQEIADTVTVMGGQDWELWLNALDEAGVLAEGCKTVAYSYIGTELTWPIYWHGAL
GKAKMDLDRAAHALNDKLAAKGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMRAEGL
HEGCMEQILRMFSERLYKADGSAPEVDEDNRLRLDDWELRDDIQQHCRDLWPQITTENLP
ELTDYFEYKAEFIKLFGFGIEGIDYDADVNPEVNFDVIEL