Protein Info for Sama_1200 in Shewanella amazonensis SB2B

Annotation: pyridoxal-dependent decarboxylase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 TIGR03799: putative pyridoxal-dependent aspartate 1-decarboxylase" amino acids 21 to 545 (525 residues), 928.1 bits, see alignment E=6.4e-284 PF00282: Pyridoxal_deC" amino acids 80 to 456 (377 residues), 161.7 bits, see alignment E=3.5e-51 PF00266: Aminotran_5" amino acids 230 to 367 (138 residues), 24.3 bits, see alignment E=2.2e-09 PF01212: Beta_elim_lyase" amino acids 231 to 376 (146 residues), 30.7 bits, see alignment E=3.2e-11

Best Hits

Swiss-Prot: 63% identical to PANP_ALIF1: Aspartate 1-decarboxylase (panP) from Aliivibrio fischeri (strain ATCC 700601 / ES114)

KEGG orthology group: K01580, glutamate decarboxylase [EC: 4.1.1.15] (inferred from 100% identity to saz:Sama_1200)

Predicted SEED Role

"Glutamate decarboxylase, eukaryotic type (EC 4.1.1.15)" (EC 4.1.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S4V1 at UniProt or InterPro

Protein Sequence (560 amino acids)

>Sama_1200 pyridoxal-dependent decarboxylase (RefSeq) (Shewanella amazonensis SB2B)
MPPAVHKTARRDEMTEKHLRKATASEDNLLRIFTVPEAADSTLGRIEQQLSADLAGFLQD
NIAALEQPLSDIEDHFYSVEVPPQPQFVSDYVDDIMAHLVAQSVHTAAPSFIGHMTSALP
YFLLPLSKLMVGLNQNLVKIETSKAFTPMERQVLGMMHHLIYGREKDFYQGFLHSASHAL
GAFCSGGTVANITALWIARNQLLKARGNFRGVTREGLHKALKHYGWDDLAILVSERGHYS
LGKAADLLGIGRDNIISVPVDAHNKVDIDAMRVAAAQLQARNIRVMAIVGVAGTTETGNV
DPLAEMAALAKEIDCHFHVDAAWGGATLLSEKYRYLLSGIELADSVTIDAHKQMYVPMGA
GMVLFKNPSFASAIEHHAEYILRQGSKDLGSQTLEGSRPGMAMLVHACLNIIGREGYEIL
INGSLERARFFAGLIEAQTDFELISEPELCLLTYRYVPAKVRLALAQAVAQHDKDKLDAI
GSLLDDLTRAIQKTQREQGKSFVSRTRITPKRYGNDKRTVFRVVLANPLTTEAILAAVLE
EQRALASGETEILQALDALC