Protein Info for Sama_0944 in Shewanella amazonensis SB2B

Updated annotation (from data): N-acetylglucosamine kinase (EC 2.7.1.59)
Rationale: Specifically important for: N-Acetyl-D-Glucosamine. This is the first step in NAG utilization (SEED_correct)
Original annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01869: BcrAD_BadFG
  • amino acids 13 to 291 (279 residues), 98.8 bits, E=2e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0944)

Predicted SEED Role

"N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59)" in subsystem Chitin and N-acetylglucosamine utilization (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (3/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.59

Use Curated BLAST to search for 2.7.1.59

Sequence Analysis Tools

See A1S445 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Sama_0944 N-acetylglucosamine kinase (EC 2.7.1.59) (Shewanella amazonensis SB2B)
MAFDQTLEGQLYLGIDGGGSKCRATLYNNKLDVLGTGVAGRANPLFGLEQTFESILASTE
MALRDAGLSLNDASLLVAGLGLAGVNVPRLLADVQAWQHPFKTMYVTSDLHTACIGAHQG
GDGAVIITGTGSCGYVHVGDESLSLGGHGFALGDKGSGAWLGLRAAEHVLLQLDGFAEPT
ALTERLFANLGVSDALGIVENLAGRSSSCYATLAREVFAAADEGDKVAVGILREGAAYIS
EMARKLFTLEPARFSMIGGLAEPLQKWLDADVVARLEPSLAAPETGAVLFAIQQHNKQSA
A