Protein Info for Sama_0902 in Shewanella amazonensis SB2B

Annotation: putative Trp operon repressor (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 98 PF01371: Trp_repressor" amino acids 4 to 89 (86 residues), 99.3 bits, see alignment E=5.2e-33 TIGR01321: trp operon repressor" amino acids 4 to 81 (78 residues), 67.5 bits, see alignment E=5.4e-23

Best Hits

Swiss-Prot: 40% identical to TRPR_VIBTL: Trp operon repressor homolog (trpR) from Vibrio tasmaniensis (strain LGP32)

KEGG orthology group: K03720, TrpR family transcriptional regulator, trp operon repressor (inferred from 100% identity to saz:Sama_0902)

Predicted SEED Role

"Transcriptional repressor protein TrpR" in subsystem Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S403 at UniProt or InterPro

Protein Sequence (98 amino acids)

>Sama_0902 putative Trp operon repressor (RefSeq) (Shewanella amazonensis SB2B)
MRASWNLVLDKILTHPERDELITLFQLLLTEEERSAIAGRLKVFQLLLAGELSQRQIAAE
YQISIATITRCSNYLKHMNEAERAVIAKLIVTDPADIR