Protein Info for Sama_0864 in Shewanella amazonensis SB2B

Annotation: phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 PF01590: GAF" amino acids 18 to 152 (135 residues), 66.5 bits, see alignment E=1.1e-21 PF13492: GAF_3" amino acids 18 to 152 (135 residues), 40.3 bits, see alignment E=1.2e-13 PF13185: GAF_2" amino acids 35 to 152 (118 residues), 55.8 bits, see alignment E=1.8e-18 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 171 to 730 (560 residues), 449.4 bits, see alignment E=8.4e-139 PF05524: PEP-utilisers_N" amino acids 171 to 292 (122 residues), 85.5 bits, see alignment E=1e-27 PF00391: PEP-utilizers" amino acids 318 to 390 (73 residues), 75.7 bits, see alignment E=5.2e-25 PF02896: PEP-utilizers_C" amino acids 419 to 706 (288 residues), 324 bits, see alignment E=2.5e-100

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 100% identity to saz:Sama_0864)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.9

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S3W5 at UniProt or InterPro

Protein Sequence (744 amino acids)

>Sama_0864 phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq) (Shewanella amazonensis SB2B)
MLNTLRDITQSVASAHTLELALESLVGQTKAAMETECCSIYILEQQQLVLSATDGLEKSA
VGRVKMPLSEGLVGLVAQREEAINLADAHLHPRFKLFPEANEDEYRAFLAAPIIYQKQLL
GVIVVQQAKARQFNEGEEAFLMTLAAQLAMAIRGLKRRAEVHSLDHQVLFTGTSASTGVA
IAHALVIGGEISLEQPEACATDVDAEVNRLRLAMGRSRDALTALAQKFENDHDDELSSIF
TSLQSLLEDASLGGEYQREVLAGWSAETAVSRVSLRYVAQFETMEDAYLRERASDIRDLG
QRVLRQLIEPGRMMLDPDKPVILVTREADTSMLAEFPRQKLAGIVTEAGGVNSHAAILAR
ALGVPAIMGVEQVLQANLDKQLLVLNASRGILMVSPSPTVVDEYRNLISAQKALDRQYAE
ELKEPALTLDGHRIHLYLNAGLMSGVSSEIADGADGVGLYRTEIPFMLQQRFPSESEQIK
VYRSVLQSAAGRPVVMRTLDVGGDKPLPYFPISEENPFLGWRGIRLSLDHPELFLVQLRA
MLQAAGDTDNLKILLPMVSSLDEIDEALLYLDQAFSELRADVNPSLARPPVGVMLEVPAL
LYQLREVAQRVEFVSVGSNDLTQYLLAVDRNNPRVSSLYDSYHPGVLRALQLALQECRQH
KLDVSVCGELAGEPMGALLLVAMGYDELSMNQGSLAKINYLLRRVERSELEQLLALVMQM
SNGQDVRELVREYLDTRELSSILG