Protein Info for Sama_0860 in Shewanella amazonensis SB2B

Annotation: LysR family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 PF00126: HTH_1" amino acids 25 to 84 (60 residues), 58.3 bits, see alignment E=5.8e-20 PF03466: LysR_substrate" amino acids 111 to 307 (197 residues), 118.6 bits, see alignment E=2.5e-38

Best Hits

KEGG orthology group: K04761, LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator (inferred from 100% identity to saz:Sama_0860)

Predicted SEED Role

"Hydrogen peroxide-inducible genes activator" in subsystem DNA-binding regulatory proteins, strays or Oxidative stress or Thioredoxin-disulfide reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S3W1 at UniProt or InterPro

Protein Sequence (323 amino acids)

>Sama_0860 LysR family transcriptional regulator (RefSeq) (Shewanella amazonensis SB2B)
MLKCKVSYQSIQAAVIGKMKHLPSLKNLYYLVNLYQEQNFNRAAKVCNVSQSTLSSGIQN
LEEQLGHQLIERDHKSFMFTAIGEEVVGRCRKILTDVDDLVELVRNQGEPMTGEIRLGCI
PTIAPFLLSRVVRHCQQHYPNMVLLLKEDTTERLLDALGKGELDLLLLALPVDTSGFHSM
KVGVDPFKMVMHKDLSHEVHQPVDYQALPDESIFLLQNEHCITGHAISACQLGDSNKINP
FAATSLHTLVQMVNSKLGTTFLPQMAIDAGILKDTELAVMDPPGSAPYRDIGLVWRQTTS
RIRTFRTLGLEIEKLLGGESRQG